(+)-Pinocembrin
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(+)-Pinocembrin
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CAS No:
480-39-7
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Formula:
C15H12O4
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Chemical Name:
(+)-Pinocembrin
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Synonyms:
4H-1-Benzopyran-4-one,2,3-dihydro-5,7-dihydroxy-2-phenyl-,(2S)-;Pinocembrin;4H-1-Benzopyran-4-one,2,3-dihydro-5,7-dihydroxy-2-phenyl-,(S)-;(2S)-2,3-Dihydro-5,7-dihydroxy-2-phenyl-4H-1-benzopyran-4-one;Galangin flavanone;Dihydrochrysin;5,7-Dihydroxyflavanone;NSC 279005;(+)-Pinocembrin;(+)-Pinocoembrin;(2S)-Pinocembrin;(2S)-5,7-Dihydroxy-2-phenyl-2,3-dihydrochromen-4-one;36052-36-5;58904-42-0
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CAS No:
Description
Pinocembrin ((+)-Pinocoembrin) is a flavonoid found in propolis, acts as a competitive inhibitor of histidine decarboxylase, and is an effective anti-allergic agent, with antioxidant, antimicrobial and anti-inflammatory properties[1].
(+)-Pinocembrin Use and Manufacturing
Pinocembrin is a flavanoid with antioxidant activity found in damiana, honey, and propolis. Recent studies show that Pinocembrin maybe be a therapeutic option in reducing cerebral ischemia/reperfusion injury as a result of its anti-oxidative and anti-apoptotic effects. Pinocembrin displayed neuroprotective effects in glutamate injury model partly by inhibiting p53 expression causing a lower Bax-Bcl-2 ratio and by inhibiting the release of cytochrome c.
Computed Properties
Molecular Weight:256.25
XLogP3:2.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:256.07355886
Monoisotopic Mass:256.07355886
Topological Polar Surface Area:66.8
Heavy Atom Count:19
Complexity:337
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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