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(-)-Borneol

(-)-Borneol structure

CAS No:
464-45-9
Formula:
C10H18O
Chemical Name:
(-)-Borneol
Synonyms:
Bicyclo[2.2.1]heptan-2-ol,1,7,7-trimethyl-,(1S,2R,4S)-;Borneol,(1S,2R,4S)-(-)-;Bicyclo[2.2.1]heptan-2-ol,1,7,7-trimethyl-,(1S-endo)-;(1S,2R,4S)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol;(-)-Borneol;Linderol;Ngai camphor;l-Borneol;(-)-(1S,4S)-Borneol;(2R)-(-)-Borneol;(1S,2R,4S)-Borneol;(-)-endo-Borneol;L-Borneol;endo-(-)-Borneol;(1S)-(-)-Borneol;(1S)-endo-Borneol;(1S)-endo-(-)-Borneol;(-)-[(1S)-endo]-Borneol;endo-(1S)-(-)-Borneol;Camphyl alcohol;(1S)-endo-(-)-Borneol;95650-45-6;1140588-66-4;2350248-19-8
Categories:
Natural Products > Terpenes

Description

(-)-Borneol has a highly efficacious positive modulating action at GABA receptor with an EC50 of 237 μM.

(-)-Borneol, is used in traditional Chinese medicine as moxa. It is a component of many essential oils, and can be also used as natural insect repellent.

(-)-Borneol Basic Attributes

Molecular Weight：

154.25

Exact Mass：

154.25

BRN：

3587558

EC Number：

207-353-1

HScode：

29061900

Characteristics

PSA：

20.2

XLogP3：

2.69

Appearance：

White to light yellow Crystalline Powder or Crystals

Density：

1.0±0.1 g/cm3

Melting Point：

207 °C

Boiling Point：

210 °C

Flash Point：

150 °F

Refractive Index：

1.502

Water Solubility：

H2O: INsoluble

Storage Conditions：

Flammables area

Vapor Pressure：

33.5 mm Hg ( 25 °C)

Vapor Density：

5.31 (vs air)

Toxicity：

LD50 orally in Rabbit: 5800 mg/kg

Specific rotation：

-36.2 º (c=5, C2H5OH)

Odor：

Piney, camphor-like odor

Taste：

Burning taste somewhat reminiscent of mint

Safety Information

Packing level：

III

Hazard category：

4.1

Transport codes：

UN 1312 4.1/PG 3

wgk germany：

hazard class code：

11-43

safety instructions：

16-36/37

RTECS Number：

DT5095000

Marks：

F,Xi

Stability/Shelf Life：

Stable at room temperature in closed containers under normal storage and handling conditions.

Precautionary statement(s)：

P210-P280

Hazard Statements：

H228-H317

RIDADR：

UN 1312

(-)-Borneol Use and Manufacturing

A bicyclic monoterpene found in essential oils has been used to study its anti-apoptotic, antioxidant and neuroprotective effects in human neuroblastoma cells (SH-SY5Y).

Analysis Methods

Name	Column Shape	Active Phase(℃)	Retention index	Method	Comments	Reference
Kovats' RI, non-polar column, temperature ramp	Capillary	BP-1	1160.	temperature ramp	H2, 65. C @ 2. min, 5. K/min; Column length: 50. m; Column diameter: 0.33 mm; T_end: 220. C	Ekundayo, O.Laakso, I.Adegbola, R.-M.Oguntimein, B.Sofowora, A.Hiltunen, R.Essential oil constituents of Ashanti pepper (Piper guineense) fruits (berries)J. Agric. Food Chem.1988, 36, 5, 880-882.
Kovats' RI, non-polar column, temperature ramp	Capillary	HP-5MS	1152.	temperature ramp	30. m/0.25 mm/0.25 μm, He, 60. C @ 5. min, 4. K/min; T_end: 280. C	Saroglou, V.Dorizas, N.Kypriotakis, Z.Skaltsa, H.D.Analysis of the essential oil composition of eight Anthemis species from GreeceJ. Chromatogr. A2006, 1104, 1-2, 313-322.
Kovats' RI, non-polar column, temperature ramp	Capillary	DB-5MS	1173.	temperature ramp	30. m/0.25 mm/0.25 μm, He, 40. C @ 5. min, 4. K/min, 200. C @ 20. min	Yu, E.J.Kim, T.H.Kim, K.H.Lee, H.J.Characterization of aroma-active compounds of Abies nephrolepis (Khingan fir) needles using aroma extract dilution analysisFlavour Fragr. J.2004, 19, 1, 74-79.
Kovats' RI, non-polar column, temperature ramp	Capillary	DB-Wax	1675.	temperature ramp	30. m/0.25 mm/0.25 μm, He, 40. C @ 5. min, 4. K/min, 200. C @ 20. min	Yu, E.J.Kim, T.H.Kim, K.H.Lee, H.J.Characterization of aroma-active compounds of Abies nephrolepis (Khingan fir) needles using aroma extract dilution analysisFlavour Fragr. J.2004, 19, 1, 74-79.
Kovats' RI, non-polar column, temperature ramp	Capillary	OV-1	1124.	temperature ramp	30. m/0.25 mm/0.25 μm, Helium, 6. K/min; T_start: 65. C; T_end: 260. C	Wang, Y.Yi, L.Liang, Y.Li, H.Yuan, D.Gao, H.Zeng, M.Comparative analysis of essential oil components in Pericarpium Citri Reticulatae Viride and Pericarpium Citri Reticulatae by GC-MS combined with chemometric resolution methodJ. Pharmaceutical and Biomedical Anal.2008, 46, 1, 66-74.

Synthesis Route

88390-69-6

100703-54-6

87614-57-1

54384-77-9

464-45-9

Suppliers(78)

Drug Function and Efficacy

Resolving phlegm and relieving qi

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Liqi Huoxue dripping pills
Ingredients	Litsea cubeba, Artemisia annua, Ligusticum chuanxiong, Allium macrostemon.
Indication	If used with other drugs, drug interactions may occur. Please consult your doctor or pharmacist for details.
Specifications	Each pill weighs 25mg
Manufacturer	Guizhou National Pharmacy Co., Ltd.

Zhupo Houzao powder
Ingredients	Poria, mint, Uncaria rhynchophylla, double flower, Saposhnikovia divaricata, Shenqu, malt, Rhizoma Cibotii, licorice, plum slices, pearl, amber, and monkey date.
Indication	Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.
Specifications	0.3g/bottle

Zhupo Houzao powder
Ingredients	Poria, mint, Uncaria rhynchophylla, double flower, Saposhnikovia divaricata, Shenqu, malt, Rhizoma Cibotii, licorice, plum slices, pearl, amber, and monkey date.
Indication	Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.
Specifications	0.3g per bottle

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Registered Holders

Jiangsu Xiansheng Biomedical Co., Ltd.

China
Active
Fujian South Pharmaceutical Co., Ltd.

China
Active
Simcere Pharmaceutical Co., Ltd.

China
Active

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Recommended Suppliers of (-)-Borneol

Hefei Heyu Chemical New Materials Co., Ltd Contact Supplier

CN
4 YRS

Business licensed

Trader Supplier of 13-Dimethyladamantane,1-Bromo-35-dimethyladamantane,perhydroacenaphthylene,4-[1,1-bis(4-hydroxyphenyl)ethyl]phenol,CYCLOBUTANE-1,2-DICARBOXYLIC ACID DIMETHYL ESTER, TRANS

L(-)-Borneol 464-45-9

CAS No.: 464-45-9

Inquiry
Hangzhou Chungyo Chemicals Co., Ltd. Contact Supplier

CN
3 YRS

Business licensed Certified factory

Manufactory Supplier of Dyes,Textile agent,Medical intermediate,API,Pigments,Basic Chemicals

L(-)-Borneol 98

CAS No.: 464-45-9

Grade: Industrial Grade

Content: 99%

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Guide of (-)-Borneol

Description
Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Analysis Methods
Synthesis Route
Drug Function and Efficacy
Related Drugs
Registered Holders
Recommended Suppliers
Learn More Other Chemicals

(-)-Borneol

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