 Home > Encyclopedia > Orphenadrine citrate

Orphenadrine citrate

Orphenadrine citrate structure

CAS No:
4682-36-4
Formula:
C18H23NO.C6H8O7
Chemical Name:
Orphenadrine citrate
Synonyms:
Ethanamine,N,N-dimethyl-2-[(2-methylphenyl)phenylmethoxy]-,2-hydroxy-1,2,3-propanetricarboxylate (1:1);Ethylamine,N,N-dimethyl-2-[(o-methyl-α-phenylbenzyl)oxy]-,citrate (1:1);Norflex (pharmaceutical);Orphenadrine citrate;Plenactol;Norflex;X-Otag;Banflex;2-Hydroxypropane-1,2,3-tricarboxylic acid dimethyl([2-[(2-methylphenyl)(phenyl)methoxy]ethyl])amine;4596-23-0
Categories:
Biochemical Engineering > Inhibitors

Description

Orphenadrine citrate is a NMDA receptor antagonist with Ki of 6.0 +/- 0.7 μM, HERG potassium channel blocker.Target: NMDA ReceptorOrphenadrine has been used as an antiparkinsonian, antispastic and analgesic drug. Orphenadrine inhibits [3H]MK-801 binding to the phencyclidine (PCP) binding site of the N-methyl-D-aspartate (NMDA)-receptor in homogenates of postmortem human frontal cortex with a Ki-value of 6.0 +/- 0.7 microM. The NMDA receptor antagonistic effects of orphenadrine were asses

Orphenadrine citrate Basic Attributes

Molecular Weight：

461.5

Exact Mass：

461.20500

EC Number：

225-137-5

HScode：

2922190900

Characteristics

PSA：

145

Density：

1.014 g/cm3

Melting Point：

137 °C @ Solvent: Methanol

Boiling Point：

363°C at 760 mmHg

Flash Point：

107.1ºC

Water Solubility：

>69.2 [ug/mL]

Storage Conditions：

2-8°C

Safety Information

Packing level：

Ⅲ

Hazard category：

6.1(b)

Transport codes：

3249

wgk germany：

hazard class code：

22-40-20/21/22

safety instructions：

22-36-62-38-36/37/39-28-26-24/25

Marks：

Xn,Xi

Precautionary statement(s)：

P281

Hazard Statements：

H302-H351

Orphenadrine citrate Use and Manufacturing

Muscle relaxant (skeletal); antihistaminic

Computed Properties

Molecular Weight:461.5
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:10
Exact Mass:461.20496695
Monoisotopic Mass:461.20496695
Topological Polar Surface Area:149
Heavy Atom Count:33
Complexity:500
Undefined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

Recommended Suppliers of Orphenadrine citrate

Hainan Flying International Trade Co., L Contact Supplier

CN
3 YRS

Business licensed

Trader Supplier of vitamin

Orphenadrine citrate 4682-36-4

CAS No.: 4682-36-4

Grade: Pharmaceutical Grade

Content: 99%

Inquiry
Shandong zhishang chemical Co.,Ltd Contact Supplier

CN
5 YRS

Business licensed Certified factory

Manufactory Supplier of Dichloromethane,Linocaine hydrochloride

High Quality CAS 4682-36-4 Orphenadrine Citrate

CAS No.: 4682-36-4

Inquiry
Shandong Airuike Chemical Co., Ltd. Contact Supplier

CN
3 YRS

Business licensed

Trader Supplier of api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals,CATALYST AND AUXILIARY,FLAVORS AND FRAGRANCES,Chemical Pesticides,ADDITIVE

4682-36-4

CAS No.: 4682-36-4

Grade: Pharmaceutical Grade

Content: 99%

Inquiry
Shandong Ailike New Material Technology Contact Supplier

CN
2 YRS

Business licensed

Trader Supplier of API,Antibiotics,Anti cancer category

High quality and low price CAS 4682-36-4 Orphenadrine Citrate

CAS No.: 4682-36-4

Grade: pharmaceutical grade

Content: 99.9%

Inquiry