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Antiradon

Antiradon structure

CAS No:
56-10-0
Formula:
C3H9N3S.2BrH
Chemical Name:
Antiradon
Synonyms:
Carbamimidothioic acid,2-aminoethyl ester,hydrobromide (1:2);Pseudourea,2-(2-aminoethyl)-2-thio-,dihydrobromide;Carbamimidothioic acid,2-aminoethyl ester,dihydrobromide;S-(2-Aminoethyl)isothiuronium bromide hydrobromide;S-(β-Aminoethyl)isothiuronium bromide hydrobromide;2-(2-Aminoethyl)-2-thiopseudourea hydrobromide;Antiradon;Surrectan;2-(β-Aminoethyl)isothiuronium bromide hydrobromide;AET;2-(2-Aminoethyl)-2-thiopseudourea dihydrobromide;NSC 22877;Ixecur;2-(2-Aminoethyl)isothiourea dihydrobromide;927-71-9
Categories:
Active Pharmaceutical Ingredients > Nervous System Drugs

Description

Crystals, hygroscopic.

A radiation-protective agent that can inhibit DNA damage by binding to the DNA. It also increases the susceptibility of blood cells to complement-mediated lysis.

Antiradon Basic Attributes

Molecular Weight：

281.01

Exact Mass：

278.904022

BRN：

3911163

EC Number：

200-257-0

UNII：

03K18418PY

DSSTox ID：

DTXSID1058765

HScode：

29309098

Characteristics

PSA：

101.19000

XLogP3：

2.98830

Density：

1.94 g/cm³

Melting Point：

181-182 °C

Boiling Point：

231.1ºC at 760mmHg

Flash Point：

93.6ºC

Water Solubility：

H2O: almost transparency

Storage Conditions：

Store below +30°C.

Toxicity：

Peritoneal-rat LD50: 288mg/kg; peritoneal-mouse LD50: 400 mg/kg

Flammability characteristics：

Flammable; burning produces toxic nitrogen oxides, hydrogen bromide and sulfur oxide fumes

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

22-36/37/38

safety instructions：

26-36/37-22

RTECS Number：

UM0175000

Marks：

Storage features：

Warehouse ventilated, low temperature and dry

Precautionary statement(s)：

P261-P305 + P351 + P338

Hazard Statements：

H302-H315-H319-H335

GHS Classification：

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 43 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Toxicity

Toxicity class：

moderately toxic

Drug Information

MeSH：

Drugs used to protect against ionizing radiation. They are usually of interest for use in radiation therapy but have been considered for other purposes, e.g. military. (See all compounds classified as Radiation-Protective Agents.)

MeSH Entry Terms：

2 Aminoethylisothiuronium Bromide

Antiradon Use and Manufacturing

Uses

NOS inhibitor

Manufacturing Info：

Carbamimidothioic acid, 2-aminoethyl ester, hydrobromide (1:2): ACTIVE

Computed Properties

Molecular Weight:281.02
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:280.90199
Monoisotopic Mass:278.90404
Topological Polar Surface Area:101
Heavy Atom Count:9
Complexity:63.2
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes

Material

Ethanolamine

Drug Function and Efficacy

This product is a drug that promotes the metabolism of central nervous cells. Its mechanism of action is that the active thiol groups released in the body participate in the redox process of brain cells, thereby promoting and restoring the metabolism of brain cells and quickly restoring metabolic function. In addition, it also has the effect of counteracting central nervous system drugs.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

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Registered Holders

Shanghai SPH New ASIA Pharmaceutical Co., Ltd.

China
Active
Jiuquan Dadeli Pharmaceutical Co., Ltd.

China
Active
Hainan General Alliance Pharmaceutical Co., Ltd.

China
Active

See More Registered Holders

Recommended Suppliers of Antiradon

Shenyang NewCathayone Tech Co., Ltd. Contact Supplier

CN
1 YR

Business licensed

Trader Supplier of Fosfomycin

NewCathayone 2-(2-Aminoethyl)Isothiourea Dihydrobromide

CAS No.: 56-10-0

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