Tetraethylammonium chloride
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Tetraethylammonium chloride
structure -
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CAS No:
56-34-8
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Formula:
C8H20N.Cl
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Chemical Name:
Tetraethylammonium chloride
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Synonyms:
Ethanaminium,N,N,N-triethyl-,chloride (1:1);Tetraethylammonium chloride;Ammonium,tetraethyl-,chloride;Ethanaminium,N,N,N-triethyl-,chloride;Etamon chloride;TEA chloride;TEAC;TEA;TEAC 100;TEAC 10W
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CAS No:
Description
white crystalline powder
Tetraethylammonium chloride is a quarternary ammonium chloride salt in which the cation has four ethyl substituents around the central nitrogen. It has a role as a potassium channel blocker. It is a quaternary ammonium salt and an organic chloride salt. It contains a tetraethylammonium.|A potassium-selective ion channel blocker. (From J Gen Phys 1994;104(1):173-90)
Tetraethylammonium chloride Basic Attributes
165.7
165.128433
200-267-5
8B82Z83XNN
DTXSID6041137
29239000
Characteristics
0
-3.15 (LogP)
white to light yellow Crystalline Powder
1.08
360 °C (decomp)
soluble in water, ethanol, chloroform, or acetone;methanol: 0.1 g/mL, clear, colorless
Store at RT
LD50 i.v. in dogs: 55.7-72.4 mg/kg (Keith, Jr.)
Safety Information
NONH for all modes of transport
3
22-36/37/38
26-36-37/39
BS6125000
Xn,Xi
Stable. Incompatible with strong oxidizing agents. Protect from moisture.
P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, P501
H302
|Warning|H302 (35.71%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 70 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Drug Information
A class of drugs that act by inhibition of potassium efflux through cell membranes. Blockade of potassium channels prolongs the duration of ACTION POTENTIALS. They are used as ANTI-ARRHYTHMIA AGENTS and VASODILATOR AGENTS. (See all compounds classified as Potassium Channel Blockers.)
Bromide, Tetraethylammonium
Tetraethylammonium chloride Use and Manufacturing
Phase transfer catalyst for polymerization. The membrane carries electrolytes for research. Examine antimony and bismuth to determine gold. Polarographic analysis. Block K+ channels; block acetylcholine neurotransmitters by blocking receptor-mediated K+ flow.
Intermediates
All other basic organic chemical manufacturing|Ethanaminium, N,N,N-triethyl-, chloride (1:1): ACTIVE
Computed Properties
Molecular Weight:165.70
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:165.1284273
Monoisotopic Mass:165.1284273
Heavy Atom Count:10
Complexity:47.5
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
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