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Benzenesulfonamide, 4-amino-N-(4-methyl-2-pyrimidinyl)-, sodium salt (1:1)

Benzenesulfonamide, 4-amino-N-(4-methyl-2-pyrimidinyl)-, sodium salt (1:1) structure

CAS No:
127-58-2
Formula:
C11H12N4O2S.Na
Chemical Name:
Benzenesulfonamide, 4-amino-N-(4-methyl-2-pyrimidinyl)-, sodium salt (1:1)
Synonyms:
Benzenesulfonamide,4-amino-N-(4-methyl-2-pyrimidinyl)-,sodium salt (1:1);Sulfanilamide,N1-(4-methyl-2-pyrimidinyl)-,monosodium salt;Benzenesulfonamide,4-amino-N-(4-methyl-2-pyrimidinyl)-,monosodium salt;Sodium,[N1-(4-methyl-2-pyrimidinyl)sulfanilamido]-;Sulfamerazine,sodium deriv.;Monosodium 2-sulfanilamido-4-methylpyrimidine;Sodium sulfamerazine;Soluble sulfamerazine;Sulfamerazine sodium;2-Sulfanilamido-4-methylpyrimidine sodium salt;4-Methyl-2-sulfanilamidopyrimidine sodium salt;Solumedine;Sulfamerazine sodium Salt
Categories:
Active Pharmaceutical Ingredients > Synthetic Anti-infective Drugs

Description

Sulfamerazine Sodium is a sulfonamide antibacterial.Target: AntibacterialSulfamerazine, the monomethyl derivative of sulfadiazine, is 2-sulfanilamido-4-methylpyrimidine. Sulfamerazine is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for binding to dihydropteroate synthetase (dihydrofolate synthetase). Sulfamerazine is bacteriostatic in nature. Inhibition of dihydrofolic acid synthesis decreases the synthesis of b

Sulfamerazine Sodium is a sodium salt form of sulfamerazine, a long-acting sulfanilamide antibacterial agent.

Benzenesulfonamide, 4-amino-N-(4-methyl-2-pyrimidinyl)-, sodium salt (1:1) Basic Attributes

Molecular Weight：

286.29

Exact Mass：

286.050049

EC Number：

204-851-0

UNII：

JOV4UJY07O

DSSTox ID：

DTXSID1051644

NCI Thesaurus Code：

C80794

Characteristics

PSA：

97.56000

XLogP3：

2.68880

Melting Point：

216-219 °C

Boiling Point：

519.1ºC at 760mmHg

Flash Point：

267.8ºC

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

20/22-36/38-36/37/38

safety instructions：

7-24-45-36-26

RTECS Number：

WP0760000

Marks：

Xn,Xi

Precautionary statement(s)：

P305 + P351 + P338

Hazard Statements：

H302-H315-H319-H332

GHS Classification：

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, and P501|Aggregated GHS information provided by 42 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Benzenesulfonamide, 4-amino-N-(4-methyl-2-pyrimidinyl)-, sodium salt (1:1) Use and Manufacturing

Uses

Involved in characterization of chirosan membranes for the transport of drugs1,2,3

Manufacturing Info：

Benzenesulfonamide, 4-amino-N-(4-methyl-2-pyrimidinyl)-, sodium salt (1:1): INACTIVE

Computed Properties

Molecular Weight:286.29
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:286.05004106
Monoisotopic Mass:286.05004106
Topological Polar Surface Area:95.3
Heavy Atom Count:19
Complexity:365
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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CAS No.: 127-58-2

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Guide of Benzenesulfonamide, 4-amino-N-(4-methyl-2-pyrimidinyl)-, sodium salt (1:1)

Description
Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
Latest News
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Benzenesulfonamide, 4-amino-N-(4-methyl-2-pyrimidinyl)-, sodium salt (1:1)

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