 Home > Encyclopedia > Diminazene

Diminazene

Diminazene structure

CAS No:
536-71-0
Formula:
C14H15N7
Chemical Name:
Diminazene
Synonyms:
Benzenecarboximidamide,4,4′-(1-triazene-1,3-diyl)bis-;Benzamidine,4,4′-(diazoamino)di-;4,4′-(1-Triazene-1,3-diyl)bis[benzenecarboximidamide];1,3-Bis(p-amidinophenyl)triazene;4,4′-Diamidinodiazoaminobenzene;Diminazene;WR 27800;MP 601206;859758-12-6
Categories:
Active Pharmaceutical Ingredients > Antiparasitic Drugs

Description

ChEBI: A triazene derivative that is triazene in which each of the terminal nitrogens is substituted by a 4-carbamimidoylphenyl group.

Diminazene is a triazene derivative that is triazene in which each of the terminal nitrogens is substituted by a 4-carbamimidoylphenyl group. It has a role as an antiparasitic agent and a trypanocidal drug. It is a triazene derivative and a carboxamidine. It is a conjugate base of a diminazene(2+).|Diminazene, also known as Diminazine, 4,4'-(Diazoamino)benzamidine, 4,4'-(1-triazene-1,3-diyl)bis-benzenecarboximidamide, diminazine aceturate, or Diminazene aceturate, is a trypanocidal agent. Major brands of Diminazene are Berenil, Pirocide, Ganasag, and Azidin. This substance is a solid. This compound belongs to the phenylhydrazines. These are compounds containing a phenylhydrazide moiety, which consists of a hydrazide substituent attached to a phenyl group. Known drug targets of diminazene include HTH-type transcriptional regulator QacR, trypsin-1, amiloride-sensitive amine oxidase [copper-containing], and mitochondrial peroxiredoxin-5.|An effective trypanocidal agent.

Diminazene Basic Attributes

Molecular Weight：

281.3158

Exact Mass：

281.32

EC Number：

208-644-6

UNII：

Y5G36EEA5Z

DSSTox ID：

DTXSID7043792

HScode：

2928000090

Characteristics

PSA：

137

XLogP3：

1.64

Appearance：

yellow to orange powder

Density：

1.4±0.1 g/cm3

Melting Point：

212 - 214ºC

Boiling Point：

463.3±55.0 °C at 760 mmHg

Flash Point：

234.0±31.5 °C

Refractive Index：

1.707

Safety Information

GHS Classification：

|Danger|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P260, P264, P270, P280, P302+P352, P307+P311, P314, P321, P332+P313, P362, P405, and P501|Aggregated GHS information provided by 35 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH：

Agents destructive to the protozoal organisms belonging to the suborder TRYPANOSOMATINA. (See all compounds classified as Trypanocidal Agents.)

MeSH Entry Terms：

4,4' Diazoaminobenzamidine

Diminazene Use and Manufacturing

Uses

Veterinary Drug -> TRYPANOCIDE; -> JECFA Functional Classes

Food Additive Classes：

Veterinary Drug -> TRYPANOCIDE;

Computed Properties

Molecular Weight:281.32
XLogP3:1.9
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:281.13889351
Monoisotopic Mass:281.13889351
Topological Polar Surface Area:137
Heavy Atom Count:21
Complexity:390
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of Diminazene

Shaanxi TNJONE Pharmaceutical Co., Ltd Contact Supplier

CN
3 YRS

Business licensed Certified factory

Manufactory Supplier of Semaglutide,Tirzepatide,API,Vitamins,Food Additive

Veterinary Drugs Raw Material CAS 536-71-0 Diminazene Powder

Unit Price: $20-25 /KG FOB

CAS No.: 536-71-0

Grade: Pharmaceutical Grade

Content: 99%

Inquiry
Wuhan Pnq Int Trade Co., Ltd Contact Supplier

CN
3 YRS

Business licensed

Trader Supplier of Apigenin,PQQ,NMNH

Veterinary Drugs Raw Material CAS 536-71-0 Diminazene

Unit Price: $5.05-6.06 /KG FOB

CAS No.: 536-71-0

Grade: Chemical Grade

Content: 99%

Inquiry
Changzhou Xuanming Pharmaceutical Techno Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of Peptides,Chemicals,API,Additives

Hot Sale Diminazene 536-71-0

CAS No.: 536-71-0

Grade: Pharmaceutical Grade

Content: 99%

Inquiry
Hubei Marvel-Bio Medicine Co., Ltd.-MZ Contact Supplier

CN
3 YRS

Business licensed

Trader Supplier of Tris,Octorylene

Animal Parasite Drug Diminazene Aceturate Injection Veterinary Drug

Unit Price: $10-12 /KG FOB

Inquiry
Shandong Airuike Chemical Co., Ltd. Contact Supplier

CN
3 YRS

Business licensed

Trader Supplier of api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals,CATALYST AND AUXILIARY,FLAVORS AND FRAGRANCES,Chemical Pesticides,ADDITIVE

diminazene 536-71-0

CAS No.: 536-71-0

Grade: Pharmaceutical Grade

Content: 99%

Inquiry