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(-)-Norepinephrine (+)-bitartrate

(-)-Norepinephrine (+)-bitartrate structure

CAS No:
51-40-1
Formula:
C8H11NO3.C4H6O6
Chemical Name:
(-)-Norepinephrine (+)-bitartrate
Synonyms:
1,2-Benzenediol,4-[(1R)-2-amino-1-hydroxyethyl]-,(2R,3R)-2,3-dihydroxybutanedioate (1:1);Benzyl alcohol,α-(aminomethyl)-3,4-dihydroxy-,(-)-,tartrate (1:1) (salt);1,2-Benzenediol,4-(2-amino-1-hydroxyethyl)-,(R)-,[R-(R*,R*)]-2,3-dihydroxybutanedioate (1:1) (salt);Arterenol,tartrate;1,2-Benzenediol,4-[(1R)-2-amino-1-hydroxyethyl]-,(2R,3R)-2,3-dihydroxybutanedioate (1:1) (salt);Levarterenol bitartrate;(-)-Noradrenaline acid tartrate;(-)-Noradrenaline bitartrate;Noradrenaline bitartrate;Norepinephrine bitartrate;(-)-Norepinephrine bitartrate;l-Norepinephrine bitartrate;Noradrenaline acid tartrate;l-Noradrenaline bitartrate;Norepinephrine tartrate;Noradrenaline hydrogen tartrate;(-)-Norepinephrine tartrate;(-)-Noradrenaline tartrate;Noradrenaline tartrate;(-)-Noradrenaline hydrogen tartrate;l-Noradrenaline tartrate;L-Norepinephrine D-bitartrate;(-)-Norepinephrine (+)-bitartrate;l-Noradrenaline d-bitartrate;(-)-Noradrenaline (+)-bitartrate;l-Arterenol bitartrate;Levophed bitartrate;l-Arterenol d-bitartrate;L-Noradrenaline bitartrate;L-Arterenol bitartrate;(-)-Noradrenaline hydrogen L-tartrate;Norepinephrine hydrogen tartrate;(-)-(R)-Norepinephrine bitartrate;NSC 169106;(R)-Noradrenaline bitartrate;73-98-3;350-25-4;893-91-4;2477-42-1;24868-01-7;33404-26-1
Categories:
Organic Chemistry > Amides

Description

Precursor of epinephrine that is secreted by the ADRENAL MEDULLA and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers, and of the diffuse projection system in the brain that arises from the LOCUS CERULEUS. It is also found in plants and is used pharmacologically as a sympathomimetic.

(-)-Norepinephrine (+)-bitartrate Basic Attributes

Molecular Weight：

319.26

Exact Mass：

319.090332

EC Number：

200-095-0

NSC Number：

169106|60394

HScode：

2922509090

Characteristics

PSA：

201.77000

XLogP3：

-1.33240

Appearance：

White crystalline powder

Melting Point：

102-104 °C

Boiling Point：

442.6ºC at 760 mmHg

Flash Point：

221.5ºC

Toxicity：

LD50 ivn-rat: 210 mg/kg YACHDS 7,627,79

Safety Information

Packing level：

III

Hazard category：

6.1(b)

Transport codes：

3249

safety instructions：

S22-S24/25

GHS Classification：

|Danger|H300 (95.24%): Fatal if swallowed [Danger Acute toxicity, oral]|P201, P202, P260, P262, P264, P270, P271, P280, P281, P284, P301+P310, P302+P350, P304+P340, P308+P313, P310, P320, P321, P322, P330, P361, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 42 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH：

Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. (See all compounds classified as Sympathomimetics.)|Drugs used to cause constriction of the blood vessels. (See all compounds classified as Vasoconstrictor Agents.)|Drugs that selectively bind to and activate alpha adrenergic receptors. (See all compounds classified as Adrenergic alpha-Agonists.)

MeSH Entry Terms：

Arterenol

(-)-Norepinephrine (+)-bitartrate Use and Manufacturing

Adrenergic (vasoconstrictor).

Computed Properties

Molecular Weight:319.26
Hydrogen Bond Donor Count:8
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:5
Exact Mass:319.09033112
Monoisotopic Mass:319.09033112
Topological Polar Surface Area:202
Heavy Atom Count:22
Complexity:276
Undefined Atom Stereocenter Count:3
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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Noradrenaline bitartrate

CAS No.: 51-40-1

Content: 99.00%

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Guide of (-)-Norepinephrine (+)-bitartrate

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