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Mercurochrome

Mercurochrome structure

CAS No:
129-16-8
Formula:
C20H10Br2HgO6.2Na
Chemical Name:
Mercurochrome
Synonyms:
Mercury,(2′,7′-dibromo-3′,6′-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9′-[9H]xanthen]-4′-yl)hydroxy-,sodium salt (1:2);Mercury,[2,7-dibromo-9-(o-carboxyphenyl)-6-hydroxy-3-oxo-3H-xanthen-4-yl]hydroxy-,disodium salt;Mercury,(2′,7′-dibromo-3′,6′-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9′-[9H]xanthen]-4′-yl)hydroxy-,disodium salt;Fluorescein,2′,7′-dibromo-4′-(hydroxymercuri)-,disodium salt;Spiro[isobenzofuran-1(3H),9′-[9H]xanthen]-3-one,2′,7′-dibromo-3′,6′-dihydroxy-,mercury complex;Spiro[isobenzofuran-1(3H),9′-[9H]xanthene],mercury deriv.;Asceptichrome;Aseptichrome;Chromargyre;2,7-Dibromo-4-hydroxymercurifluoresceine disodium salt;Disodium 2′,7′-dibromo-4′-(hydroxymercury)fluorescein;DOMF;Flavurol;Fluorochrome;Gallochrome;Gynochrome;Merbromin;Mercuranine;Mercurochrome;Mercurocol;Mercurome;Mercurophage;No. 220 Soluble;Planochrome;Disodium 2,7-dibromo-4-(hydroxymercuri)fluorescein;Sodium 2,7-dibromo-4-hydroxymercurifluorescein;Mercurichrome;Mercuresceine;Curichrome;Curocromo;Cynochrome;Brocasept;Lapicromo;Lafircrom;Emcerol;Mercromina film;Supercromer orto;Cinfacromin;Sodium mercurescein;No. 220 sol;Mercurochrome 220 Soluble;25295-30-1;315241-46-4;1231968-17-4
Categories:
Active Pharmaceutical Ingredients > Synthetic Anti-infective Drugs

Description

Mercurochrome is an organic mercury compound with the chemical formula C20H20HgN2O2. This compound is notable for its bright red appearance and typically exists in liquid form. Mercurochrome is widely used in the medical field due to its powerful antibacterial properties, effectively inhibiting and killing various bacteria, which plays a significant role in healthcare. It is commonly used in hospitals and clinics, as well as occupying a place in household first aid kits, becoming a preferred medication for treating minor wounds and abrasions. Mercurochrome's notable antibacterial effects can quickly reduce the risk of infection and aid in wound healing, earning it the trust and praise of many users.

Mercurochrome Basic Attributes

Molecular Weight：

750.65

Exact Mass：

752.82472

EC Number：

204-933-6

ATC Code：

D - Dermatologicals

Characteristics

PSA：

113.63000

XLogP3：

3.59240

Appearance：

green crystalline

Melting Point：

≥300 °C

Water Solubility：

In ethyleneglycol monomethyl ether, 9 mg/ml; in ethanol, 10 mg/ml, 25 °C.

Storage Conditions：

Poison room

Toxicity：

Abdominal cavity-mouse LDL0: 200 mg/kg

Flammability characteristics：

Combustible, the fire emits spicy irritating smoke containing mercury, bromide and sodium oxide

Safety Information

Packing level：

Hazard category：

6.1(a)

Transport codes：

UN 2025 6.1/PG 2

wgk germany：

hazard class code：

26/27/28-33-50/53

safety instructions：

13-28-36-45-60-61

RTECS Number：

LM5250000

Marks：

T+,N

Storage features：

Warehouse low temperature, ventilated, dry

Stability/Shelf Life：

Stable. Incompatible with strong oxidizing agents, strong acids.

Precautionary statement(s)：

P260-P273-P280-P301 + P310 + P330-P302 + P352 + P310-P304 + P340 + P310

Hazard Statements：

H300 + H310 + H330-H373-H410

GHS Classification：

|Danger|H300 (100%): Fatal if swallowed [Danger Acute toxicity, oral]|P260, P262, P264, P270, P271, P273, P280, P284, P301+P310, P302+P350, P304+P340, P310, P314, P320, P321, P322, P330, P361, P363, P391, P403+P233, P405, and P501|Aggregated GHS information provided by 43 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Toxicity

Toxicity class：

moderately toxic

Drug Information

MeSH Entry Terms：

Merbromin

Mercurochrome Use and Manufacturing

Mercurochrome is a chemical substance commonly used for skin disinfection and wound care, featuring strong antibacterial and preservative properties. Due to its effective bactericidal ability, Mercurochrome has found extensive application in the medical field, especially in treating various skin injuries and infections. However, the presence of mercury in Mercurochrome has led to certain restrictions on its use. Despite this, it remains widely used in some areas due to the lack of better alternatives or for other reasons. While the mercury content may pose some health risks, in these regions, Mercurochrome continues to be an important antibacterial agent and preservative.

Computed Properties

Molecular Weight:707.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:708.86083
Monoisotopic Mass:706.86288
Topological Polar Surface Area:84.8
Heavy Atom Count:29
Complexity:807
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

Material

Resorcinol

Drug Function and Efficacy

This product is an organic mercury disinfectant preservative. After the mercury ions dissociate, they combine with proteins to kill bacteria, but are ineffective against bacterial spores. This product has a weak preservative effect and is not easy to penetrate intact skin. However, it has less irritation to the skin.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Mercurochrome solution
Ingredients	The main ingredient of this product is mercurochrome, and its chemical name is 2,7-dibromo-4-hydroxymercury fluorescent flavin disodium salt.
Indication	Incompatible with acidic substances and iodides.
Specifications	2%
Manufacturer	SPH Qingdao Growful Pharmaceutical Co., Ltd.

Mercurochrome solution
Ingredients	The main ingredient of this product is mercurochrome, and its chemical name is 2,7-dibromo-4-hydroxymercury fluorescent flavin disodium salt.
Indication	Incompatible with acidic substances and iodides.
Specifications	2%
Manufacturer	Guangdong Nanguo Pharmaceutical Co., Ltd.

Mercurochrome solution
Ingredients	The main ingredient of this product is mercurochrome, and its chemical name is 2,7-dibromo-4-hydroxymercury fluorescent flavin disodium salt.
Indication	Incompatible with acidic substances and iodides.
Specifications	100ml

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Registered Holders

Guizhou Tongren Yinhu Chemical Co., Ltd. Pharmaceutical Factory

China
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