 Home > Encyclopedia > Tetrahydrofolic acid

Tetrahydrofolic acid

Tetrahydrofolic acid structure

CAS No:
135-16-0
Formula:
C19H23N7O6
Chemical Name:
Tetrahydrofolic acid
Synonyms:
L-Glutamic acid,N-[4-[[(2-amino-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-;L-Glutamic acid,N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-;Glutamic acid,N-[p-[[(2-amino-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-,L-;N-[4-[[(2-Amino-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid;Tetrahydrofolic acid;THFA;5,6,7,8-Tetrahydrofolic acid;Tetrahydropteroylglutamic acid;(-)-L-5,6,7,8-Tetrahydrofolic acid;L-5,6,7,8-Tetrahydrofolic acid;(2S)-2-(4-(((2-Imino-4-oxo-1,2,3,4,5,6,7,8-octahydropteridin-6-yl)methyl)amino)benzamido)pentanedioic acid;4172-42-3;14231-42-6;15582-27-1;18632-03-6;60201-89-0
Categories:
Active Pharmaceutical Ingredients > Vitamins and Minerals Medicines

Description

L-5,6,7,8-Tetrahydrofolic acid, a folic acid derivative, which is a coenzyme in many reactions, especially in the metabolism of amino acids and nucleic acids.

(6S)-5,6,7,8-tetrahydrofolic acid is a derivative of folic acid in which the pteridine ring is fully reduced; it is the parent compound of a variety of coenzymes that serve as carriers of one-carbon groups in metabolic reactions. It has a role as a cofactor. It is a conjugate acid of a (6S)-5,6,7,8-tetrahydrofolate(2-).

Tetrahydrofolic acid Basic Attributes

Molecular Weight：

445.43

Exact Mass：

445.43

EC Number：

205-181-1

HScode：

2933990090

Characteristics

PSA：

207

XLogP3：

-0.6

Appearance：

off-white to tan powder

Density：

1.7g/cm3

Refractive Index：

1.762

Storage Conditions：

−20°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

RTECS Number：

MA0600800

Stability/Shelf Life：

We have observed that this material decomposes steadily over time. Use immediately upon receipt.

GHS Classification：

|Warning|H252 (100%): Self-heating in large quantities; may catch fire [Warning Self-heating substances and mixtures]|P235+P410, P261, P272, P280, P302+P352, P321, P333+P313, P363, P407, P413, P420, and P501|Aggregated GHS information provided by 2 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Tetrahydrofolic acid Use and Manufacturing

A folic acid derivative and coenzyme involved in the metabolism of amino and nucleic acids. We have observed that this material decomposes steadily over time. Use immediately upon receipt.

Computed Properties

Molecular Weight:445.4
XLogP3:-0.6
Hydrogen Bond Donor Count:8
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:9
Exact Mass:445.17098148
Monoisotopic Mass:445.17098148
Topological Polar Surface Area:207
Heavy Atom Count:32
Complexity:834
Defined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of Tetrahydrofolic acid

LEADER BIOCHEMICAL GROUP Contact Supplier

CN
8 YRS

Business licensed Certified factory

Manufactory Supplier of Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients,Natural Plant Ingredients,APIS Intermidiates,Daily Chemicals,Agricultural Chemicals,Surfactant Chemicals,Ultraviolet Absorbents,Antioxidant Ingredients,Scientific Research Chemical,Flavors and Fragrances Chemicals

China Largest factory Manufacturer Supply High Qulity L-Tetrahydrofolic Acid CAS 135-16-0

CAS No.: 135-16-0

Grade: Pharmaceutical Grade

Content: 99%

Inquiry
Creative Enzymes Contact Supplier

US
6 YRS

Business licensed Certified factory

Manufactory Supplier of Coenzymes,Inhibito,Enzymes,Zymogens,Substrates

Tetrahydrofolic acid

CAS No.: 135-16-0

Content: 65%

Inquiry