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Home > Encyclopedia > Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-(2-propen-1-yl)-, hydrobromide (1:1), (5α,6α)-

Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-(2-propen-1-yl)-, hydrobromide (1:1), (5α,6α)-

pharmaceutical raw materials
Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-(2-propen-1-yl)-, hydrobromide (1:1), (5α,6α)- structure

Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-(2-propen-1-yl)-, hydrobromide (1:1), (5α,6α)- 

structure
  • CAS No:

    1041-90-3

  • Formula:

    C19H21NO3.BrH

  • Chemical Name:

    Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-(2-propen-1-yl)-, hydrobromide (1:1), (5α,6α)-

  • Synonyms:

    Morphinan-3,6-diol,7,8-didehydro-4,5-epoxy-17-(2-propen-1-yl)-,hydrobromide (1:1),(5α,6α)-;Morphinan-3,6α-diol,17-allyl-7,8-didehydro-4,5α-epoxy-,hydrobromide;Morphinan-3,6-diol,7,8-didehydro-4,5-epoxy-17-(2-propenyl)-,hydrobromide,(5α,6α)-;Nalorphine hydrobromide;(-)-Nalorphine hydrobromide;Nalorphine bromide;(-)-Nalorphine bromide;N-Allylnormorphine hydrobromide;860355-35-7

  • Categories:

    Active Pharmaceutical Ingredients  >  Specialty Drugs

Description

A narcotic antagonist with some agonist properties. It is an antagonist at mu opioid receptors and an agonist at kappa opioid receptors. Given alone it produces a broad spectrum of unpleasant effects and it is considered to be clinically obsolete.

Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-(2-propen-1-yl)-, hydrobromide (1:1), (5α,6α)- Basic Attributes

392.291

391.07800

213-868-2

1OLB66508A

DTXSID20146277

Characteristics

52.93000

2.65030

126 °C

493.6ºC at 760mmHg

252.3ºC

Drug Information

Agents inhibiting the effect of narcotics on the central nervous system. (See all compounds classified as Narcotic Antagonists.)

Allylnormorphine

Computed Properties

Molecular Weight:406.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:405.09396
Monoisotopic Mass:405.09396
Topological Polar Surface Area:41.9
Heavy Atom Count:25
Complexity:563
Defined Atom Stereocenter Count:5
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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