Product
Supplier
Encyclopedia
Inquiry
Home > Encyclopedia > N-(9-Fluorenylmethoxycarbonyl)-L-glutamic acid γ-tert-butyl ester

N-(9-Fluorenylmethoxycarbonyl)-L-glutamic acid γ-tert-butyl ester

N-(9-Fluorenylmethoxycarbonyl)-L-glutamic acid γ-tert-butyl ester structure

N-(9-Fluorenylmethoxycarbonyl)-L-glutamic acid γ-tert-butyl ester 

structure
  • CAS No:

    71989-18-9

  • Formula:

    C24H27NO6

  • Chemical Name:

    N-(9-Fluorenylmethoxycarbonyl)-L-glutamic acid γ-tert-butyl ester

  • Synonyms:

    L-Glutamic acid,N-[(9H-fluoren-9-ylmethoxy)carbonyl]-,5-(1,1-dimethylethyl) ester;N-(9-Fluorenylmethoxycarbonyl)-L-glutamic acid γ-tert-butyl ester;N-(9-Fluorenylmethoxycarbonyl)glutamic acid γ-tert-butyl ester;(2S)-5-tert-Butoxy-2-[[[(9H-fluoren-9-yl)methoxy]carbonyl]amino]-5-oxopentanoic acid;(2S)-5-(tert-Butoxy)-2-([[(9H-fluoren-9-yl)methoxy]carbonyl]amino)-5-oxopentanoic acid;(2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoic acid;(2S)-5-tert-Butoxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)-5-oxo-pentanoic acid;138451-82-8;184170-70-5;1017238-29-7;1123654-81-8;1349173-04-1;1385773-90-9;2096497-79-7

  • Categories:

    Pharmaceutical Intermediates  >  Antineoplastics

Description

White powder

N-(9-Fluorenylmethoxycarbonyl)-L-glutamic acid γ-tert-butyl ester Basic Attributes

425.47

425.47

276-253-8

29242970

Characteristics

102

3.9

1.2±0.1 g/cm3

83-90 °C

337.0±31.5 °C

1.571

2-8°C

-4.5 º (c=1, 80% acetic acid)

Safety Information

NONH for all modes of transport

3

36/37/38

26-27-36/37/39-24/25

Xi

P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P312, P322, P330, P363, P403+P233, P405, P501

H302

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P312, P322, P330, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 6 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

N-(9-Fluorenylmethoxycarbonyl)-L-glutamic acid γ-tert-butyl ester Use and Manufacturing

Methods of Manufacturing

Using fluorenylmethyloxycarbonyl chloride (or azide) and L-glutamic acid-5-tert-butyl ester as raw materials, the acylation reaction is carried out under alkaline conditions, and the product is obtained after crystallization and purification.

Uses

Used as an amino acid protection monomer, for peptide synthesis.

Computed Properties

Molecular Weight:425.5
XLogP3:3.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:10
Exact Mass:425.18383758
Monoisotopic Mass:425.18383758
Topological Polar Surface Area:102
Heavy Atom Count:31
Complexity:635
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

Recommended Suppliers of N-(9-Fluorenylmethoxycarbonyl)-L-glutamic acid γ-tert-butyl ester

Scan the QR Code to Share

Feedback & Suggestions
Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.