N-(9-Fluorenylmethoxycarbonyl)-L-glutamic acid γ-tert-butyl ester
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N-(9-Fluorenylmethoxycarbonyl)-L-glutamic acid γ-tert-butyl ester
structure -
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CAS No:
71989-18-9
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Formula:
C24H27NO6
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Chemical Name:
N-(9-Fluorenylmethoxycarbonyl)-L-glutamic acid γ-tert-butyl ester
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Synonyms:
L-Glutamic acid,N-[(9H-fluoren-9-ylmethoxy)carbonyl]-,5-(1,1-dimethylethyl) ester;N-(9-Fluorenylmethoxycarbonyl)-L-glutamic acid γ-tert-butyl ester;N-(9-Fluorenylmethoxycarbonyl)glutamic acid γ-tert-butyl ester;(2S)-5-tert-Butoxy-2-[[[(9H-fluoren-9-yl)methoxy]carbonyl]amino]-5-oxopentanoic acid;(2S)-5-(tert-Butoxy)-2-([[(9H-fluoren-9-yl)methoxy]carbonyl]amino)-5-oxopentanoic acid;(2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoic acid;(2S)-5-tert-Butoxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)-5-oxo-pentanoic acid;138451-82-8;184170-70-5;1017238-29-7;1123654-81-8;1349173-04-1;1385773-90-9;2096497-79-7
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CAS No:
N-(9-Fluorenylmethoxycarbonyl)-L-glutamic acid γ-tert-butyl ester Basic Attributes
425.47
425.47
276-253-8
29242970
Characteristics
102
3.9
1.2±0.1 g/cm3
83-90 °C
337.0±31.5 °C
1.571
2-8°C
-4.5 º (c=1, 80% acetic acid)
Safety Information
NONH for all modes of transport
3
36/37/38
26-27-36/37/39-24/25
Xi
P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P312, P322, P330, P363, P403+P233, P405, P501
H302
|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P312, P322, P330, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 6 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
N-(9-Fluorenylmethoxycarbonyl)-L-glutamic acid γ-tert-butyl ester Use and Manufacturing
Using fluorenylmethyloxycarbonyl chloride (or azide) and L-glutamic acid-5-tert-butyl ester as raw materials, the acylation reaction is carried out under alkaline conditions, and the product is obtained after crystallization and purification.
Used as an amino acid protection monomer, for peptide synthesis.
Computed Properties
Molecular Weight:425.5
XLogP3:3.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:10
Exact Mass:425.18383758
Monoisotopic Mass:425.18383758
Topological Polar Surface Area:102
Heavy Atom Count:31
Complexity:635
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of N-(9-Fluorenylmethoxycarbonyl)-L-glutamic acid γ-tert-butyl ester
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CN
5 YRS
Business licensedTrader Supplier of API,nutrition supplements,plant extract,peptide,HCGInquiryUnit Price: $1-1.2 /KG FOBCAS No.: 71989-18-9Grade: Top ProductContent: 99% -
CN
4 YRS
Business licensed Certified factoryManufactory Supplier of Cosmetics raw materials,Pesticide intermediate,Photoelectric material,pharmaceutical intermediates,Raw materials for food and health products,Polymer materials,Fine Chemicals,Synthetic customization -
CN
4 YRS
Business licensedTrader Supplier of Semaglutide,Tirzepatide,API,EnzymeInquiryCAS No.: 71989-18-9Grade: Pharmaceutical GradeContent: 99.5% -
CN
2 YRS
Business licensed Certified factoryManufactory Supplier of 4-(Pentafluorothio)aniline,Pentafluoro,Pentafluorothio,Pentafluorosulfur,[4-(bromomethyl)phenyl]-pentafluoro-lambda6-sulfane,[4-(pentafluoro-sulfanyl)phenyl]acetic acidInquiryCAS No.: 71989-18-9Grade: Industrial GradeContent: 95% -
CN
2 YRS
Business licensed Certified factoryManufactory Supplier of semaglutide intermediates,tirzepatide intermediate,degludec intermediate,insulin detemir,retatrutide intermediate
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N-(9-Fluorenylmethoxycarbonyl)-L-glutamic acid γ-tert-butyl ester
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