Cephalotaxine
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Cephalotaxine
structure -
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CAS No:
24316-19-6
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Formula:
C18H21NO4
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Chemical Name:
Cephalotaxine
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Synonyms:
Cephalotaxine;4H-Cyclopenta[a][1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepin-1-ol,1,5,6,8,9,14b-hexahydro-2-methoxy-,[1S-(1α,3aS*,14bβ)]-;[1S-(1α,3aS*,14bβ)]-1,5,6,8,9,14b-Hexahydro-2-methoxy-4H-cyclopenta[a][1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepin-1-ol;(-)-Cephalotaxine;NSC 128487;NSC 245454;ZINC 19795976;26909-63-7;30255-03-9
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CAS No:
Description
Cephalotaxine is an antiviral as well as antitumor agent.
LSM-1290 is a cyclic acetal and a benzazepine alkaloid.
Characteristics
51.2
0.2
White powder with faint yellow cast
1.4±0.1 g/cm3
131-132 °C @ Solvent: Benzene
495.2°C at 760 mmHg
253.3±28.7 °C
1.665
2-8°C
1.27E-10mmHg at 25°C
Safety Information
III
6.1(b)
UN 1544 6.1/PG 3
3
20/21/22
36
Xn
P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P312, P322, P330, P363, P501
H302
Cephalotaxine Use and Manufacturing
Sodium borohydride (27 mg, 0.70 mmol, 40 equiv) was added to a stirred solution of (-)-cephalotaxinone (S9) (5.5 mg, 18 μmol, 1.0 equiv) in methaol (0.65 mL) at -78
Antiviral and antitumor agent
Computed Properties
Molecular Weight:315.4
XLogP3:0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:315.14705815
Monoisotopic Mass:315.14705815
Topological Polar Surface Area:51.2
Heavy Atom Count:23
Complexity:523
Undefined Atom Stereocenter Count:3
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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