Venlafaxine hydrochloride

Venlafaxine hydrochloride is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class.Target: SNRIVenlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. First introduced by Wyeth in 1993, now marketed by Pfizer, it is licensed for the treatment of major depressive disorder (MDD), as a treatment for generalized anxiety disorder, and comorbid indications in certain anxiety disorders with depression. In 2007, venlafaxine wa

• CAS No：

  99300-78-4

• Molecular Formula ：

  C17H28ClNO2

• Molecular Mass ：

  313.86

• Exact Mass ：

  313.180847

• PSA ：

  32.7

• LogP ：

  0.43 (LogP)

• EINECS ：

  200-659-6

• InChIKeys ：

  QYRYFNHXARDNFZ-UHFFFAOYSA-N

• H-bond Acceptor ：

  3

• H-bond Donor ：

  2

• RBN ：

  5

• Appearance ：

  white

• Density ：

  1.394 g/cm3

• Melting Point ：

  207-209°C

• Flash Point ：

  9℃

• Solubility ：

  H2O: >10mg/mL

• Storage Condition ：

  Store at RT

• HS Code ：

  2922509090

• UN No. ：

  UN1230 - class 3 - PG 2 - Methanol, solution

• WGK_Germany ：

  3

• Risk Code ：

  36/37/38-36-39/23/24/25-23/24/25-11

• Safety Instructions ：

  26-37/39-45-36/37-16-7

• RTECS No. ：

  GV8872760

• Dangerous Mark ：

  Xi,T,F

• P Code ：

  P210-P260-P280-P301 + P310-P311

• Hazard Statements ：

  H225-H301 + H311 + H331-H370

Venlaxafine is an inhibitor of reuptake of both serotonin (IC50 = 0.21 μM) and norepinephrine (IC50 = 0.64 μM). It is effective in vitro and in vivo and against human as well as rat receptors. As an antidepressant, it is properly placed in the serotonin-norepinephrine reuptake inhibitor class.[Cayman Chemical]