Maneb Safety Data Sheets
SAFETY DATA SHEETS
According to the UN GHS revision 8
SECTION 1: Identification
1.1 GHS Product identifier
| Product name | Maneb |
|---|
1.2 Other means of identification
| Product number | - |
|---|---|
| Other names | Rhodianebe; Nereb; Manebgan |
1.3 Recommended use of the chemical and restrictions on use
| Identified uses | Industrial and scientific research uses. |
|---|---|
| Uses advised against | no data available |
1.4 Supplier's details
| Company | Echemi.com |
|---|---|
| Address | Echemi.com |
| Telephone | Echemi.com |
1.5 Emergency phone number
| Emergency phone number | Echemi.com |
|---|---|
| Service hours | Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours). |
SECTION 2: Hazard identification
2.1 Classification of the substance or mixture
Eye irritation, Category 2
Skin sensitization, Category 1
Acute toxicity - Category 4, Inhalation
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
Reproductive toxicity, Category 2
2.2 GHS label elements, including precautionary statements
| Pictogram(s) |    |
|---|---|
| Signal word | Warning |
| Hazard statement(s) | H319 Causes serious eye irritation H317 May cause an allergic skin reaction H332 Harmful if inhaled H410 Very toxic to aquatic life with long lasting effects |
| Precautionary statement(s) | |
| Prevention | P264 Wash ... thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P271 Use only outdoors or in a well-ventilated area. P273 Avoid release to the environment. P203 Obtain, read and follow all safety instructions before use. |
| Response | P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P302+P352 IF ON SKIN: Wash with plenty of water/... P333+P317 If skin irritation or rash occurs: Get medical help. P321 Specific treatment (see ... on this label). P362+P364 Take off contaminated clothing and wash it before reuse. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P317 Get medical help. P391 Collect spillage. P318 IF exposed or concerned, get medical advice. |
| Storage | P405 Store locked up. |
| Disposal | P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal. |
2.3 Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
3.1 Substances
| Chemical name | Common names and synonyms | CAS number | EC number | Concentration |
|---|---|---|---|---|
| Maneb | Maneb | 12427-38-2 | 235-654-8 | 100% |
SECTION 4: First-aid measures
4.1 Description of necessary first-aid measures
If inhaled
Fresh air, rest.
Following skin contact
Remove contaminated clothes. Rinse and then wash skin with water and soap.
Following eye contact
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Following ingestion
Rinse mouth. Refer for medical attention .
4.2 Most important symptoms/effects, acute and delayed
Excerpt from ERG Guide 135 [Substances - Spontaneously Combustible]: Fire will produce irritating, corrosive and/or toxic gases. Inhalation of decomposition products may cause severe injury or death. Contact with substance may cause severe burns to skin and eyes. Runoff from fire control may cause pollution. (ERG, 2016)
4.3 Indication of immediate medical attention and special treatment needed, if necessary
Immediate first aid: Remove patient from contact with the material. Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Dithiocarbamates and Related Compounds
SECTION 5: Fire-fighting measures
5.1 Suitable extinguishing media
If material on fire or involved in fire: Do not extinguish fire unless flow can be stopped. Do not use water. Use graphite, soda ash, powdered sodium chloride, or suitable dry powder. Maneb or maneb preparations stabilized
5.2 Specific hazards arising from the chemical
Excerpt from ERG Guide 135 [Substances - Spontaneously Combustible]: Flammable/combustible material. May ignite on contact with moist air or moisture. May burn rapidly with flare-burning effect. Some react vigorously or explosively on contact with water. Some may decompose explosively when heated or involved in a fire. May re-ignite after fire is extinguished. Runoff may create fire or explosion hazard. Containers may explode when heated. (ERG, 2016)
5.3 Special protective actions for fire-fighters
Use carbon dioxide, dry powder. NO hydrous agents. NO water.
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Do NOT wash away into sewer. Sweep spilled substance into covered sealable containers. Carefully collect remainder. Then store and dispose of according to local regulations.
6.2 Environmental precautions
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Do NOT wash away into sewer. Sweep spilled substance into covered sealable containers. Carefully collect remainder. Then store and dispose of according to local regulations.
6.3 Methods and materials for containment and cleaning up
SRP: Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations. Concentrations shall be lower than applicable environmental discharge or disposal criteria. Alternatively, pretreatment and/or discharge to a permitted wastewater treatment facility is acceptable only after review by the governing authority and assurance that "pass through" violations will not occur. Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal. If it is not practicable to manage the chemical in this fashion, it must be evaluated in accordance with EPA 40 CFR Part 261, specifically Subpart B, in order to determine the appropriate local, state and federal requirements for disposal.
SECTION 7: Handling and storage
7.1 Precautions for safe handling
NO open flames. NO contact with water. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
7.2 Conditions for safe storage, including any incompatibilities
Separated from acids and food and feedstuffs. Dry. Well closed. Keep in a well-ventilated room. Store only if stabilized.This product must be stored in its sealed original containers, in well-aired places. It is recommended that the product's temperature should not exceed 25-30 deg C. The containers must be stacked in such a way as to permit a free circulation of air also at the bottom & inside of the piles.
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
Occupational Exposure limit values
MAK sensitization of skin (SH)
Biological limit values
no data available
8.2 Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
8.3 Individual protection measures, such as personal protective equipment (PPE)
Eye/face protection
Wear safety goggles or eye protection in combination with breathing protection.
Skin protection
Protective gloves. Protective clothing.
Respiratory protection
Use local exhaust or breathing protection.
Thermal hazards
no data available
SECTION 9: Physical and chemical properties and safety characteristics
| Physical state | Maneb is a yellow powder or crystalline solid. It is denser than water. Contact may irritate skin, eyes and mucous membranes. It may be toxic by ingestion. Likely to generate heat spontaneously upon exposure to air or water. May be sufficient to ignite the material. Maneb is used as a fungicide. Formulations of Maneb include mixing it with many other chemicals such as sulfur, zinc oxide and others to desensitize it. This is done to make it easer for application. |
|---|---|
| Colour | Yellow powder; crystals from alcohol |
| Odour | Practically odorless |
| Melting point/freezing point | 192-204ºC (decomposes before melting) |
| Boiling point or initial boiling point and boiling range | 308.2ºC at 760 mmHg |
| Flammability | Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire. |
| Lower and upper explosion limit/flammability limit | no data available |
| Flash point | no data available |
| Auto-ignition temperature | no data available |
| Decomposition temperature | 192-204°C |
| pH | no data available |
| Kinematic viscosity | no data available |
| Solubility | Soluble in chloroform, pyridine |
| Partition coefficient n-octanol/water | log Kow = 0.62 (est) |
| Vapour pressure | 7.5X10-8 mm Hg at 25 deg C |
| Density and/or relative density | 1.92 |
| Relative vapour density | no data available |
| Particle characteristics | no data available |
SECTION 10: Stability and reactivity
10.1 Reactivity
500 mg/cu m Manganese cmpds and fume, as Mn
Decomposes on contact with acids or moisture. This produces toxic and flammable gases including hydrogen sulfide and carbon disulfide.
10.2 Chemical stability
Stable under ordinary storage conditions but decomposes more or less rapidly when exposed to moisture or to acids. In presence of moisture decomposition proceeds as in nabam with formation of polymeric ethylene thiuram monosulfide. ... The biological activity of the product remains practically unvaried for 2 yr under environmental conditions, provided the product is stored in its unopened & undamaged original containers, in shaded & possible well-aired places.
10.3 Possibility of hazardous reactions
May ignite spontaneously in air.The BPS Pesticide incident in Helena resulted in an explosion and death of three firemen. The burning of a 1,000 pound sack of Azinphos Methyl or the flashing of Maneb which was present on the facility may have caused the explosion.
10.4 Conditions to avoid
no data available
10.5 Incompatible materials
Water, acid, oxidizing materials. Heat or contact with moisture or acids causes rapid decomposition and the generation of toxic and flammable hydrogen sulfide and carbon disulfide.
10.6 Hazardous decomposition products
Decomposes without melting at 192-204 deg C. ... Decomposes on prolonged exposure to air or moisture.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat oral 6750 mg/kg
- Inhalation: LC50 Rat inhalation > 1.3 mg/L
- Dermal: LD50 Rat percutaneous > 5000 mg/kg
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
No data are available in humans. Inadequate evidence of carcinogenicity in animals. OVERALL EVALUATION: Group 3: The agent is not classifiable as to its carcinogenicity to humans.
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the eyes, skin and respiratory tract.
STOT-repeated exposure
Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the kidneys and central nervous system. This may result in kidney impairment and neurologic and neuropsychiatric disorders (manganism).
Aspiration hazard
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed.
SECTION 12: Ecological information
12.1 Toxicity
- Toxicity to fish: LC50; Species: Lepomis macrochirus (Bluegill); Conditions: freshwater, static; Concentration: <78000 ug/L for 48 hr /5.6% purity
- Toxicity to daphnia and other aquatic invertebrates: EC50; Species: Daphnia magna (Water flea, exponential growth phase); Conditions: freshwater, flow through, 20 deg C; Concentration: 60 ug/L for <1.5 days (95% confidence interval: 50-70 ug/L); Effect: population changes, general, carrying capacity /> or =90% purity
- Toxicity to algae: EC50; Species: Pseudokirchneriella subcapitata (Green algae); Conditions: freshwater, static; Concentration: 14 ug/L for 120 hr; Effect: population abundance /87.3% purity
- Toxicity to microorganisms: no data available
12.2 Persistence and degradability
AEROBIC: Approximately 90% maneb was degraded under aerobic conditions in six weeks in a field test in moist plough layer with 2-4% humus, with a pH of 5.5-6.5 under a medium air temperature of 11-16 deg C(1). In loamy sand in dark aerobic conditions, 50% maneb is degraded in 25 days(2). In a 5-day CO2 evolution study using an activated sludge inoculum, 0.6% of applied maneb (50 ppb; (14)C radiolabeled) was detected as (14)C labeled CO2(3). The effect of maneb on microorganisms in two agriculturally important soils in Puerto Rico was studied under laboratory conditions for an 18-month period(4). In general, bacterial numbers increased while actinomycetes and fungi decreased, especially at higher concns (up to 960 ppm)(4). It was postulated that bacteria are the principal microorganisms in soil responsible for maneb biodegradation(4).
12.3 Bioaccumulative potential
In a 3-day static system study, a BCF for maneb of <10 was measured in golden ide (Leuciscus idus melanotus) fish(1). According to a classification scheme(2), this BCF suggests bioconcentration in aquatic organisms is low.
12.4 Mobility in soil
The Koc for maneb is 240(1). According to a classification scheme(2), this Koc value suggests that maneb is expected to have moderate mobility in soil. Using soil thin-layer chromatography and five different soil types, the Rf value of maneb was found to range from 0 to 0.42 which indicates immobility to moderate mobility in soil(3). These higher Rf values may have resulted from a dissociation to the free ethylenebis(dithiocarbamate) or the presence of an ethylene thiourea impurity(4), otherwise, maneb can be expected to be generally immobile in soil(3). In a microagroecosystem chamber study using a Galestown sandy loam soil, spray applications of maneb did not penetrate below a 1 cm depth although unspecified soluble degradation products were collected in leachate waters(4). During a 52-week field study in Delaware where 14-C-labeled maneb was applied to a silty loam soil, radio-labeled residues did not leach below a 5 inch depth(5).
12.5 Other adverse effects
no data available
SECTION 13: Disposal considerations
13.1 Disposal methods
Product
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Contaminated packaging
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
14.1 UN Number
| ADR/RID: UN2968 (For reference only, please check.) | IMDG: UN2968 (For reference only, please check.) | IATA: UN2968 (For reference only, please check.) |
14.2 UN Proper Shipping Name
| ADR/RID: MANEB, STABILIZED or MANEB PREPARATION, STABILIZED against self-heating (For reference only, please check.) | IMDG: MANEB, STABILIZED or MANEB PREPARATION, STABILIZED against self-heating (For reference only, please check.) | IATA: MANEB, STABILIZED or MANEB PREPARATION, STABILIZED against self-heating (For reference only, please check.) |
14.3 Transport hazard class(es)
| ADR/RID: 4.3 (For reference only, please check.) | IMDG: 4.3 (For reference only, please check.) | IATA: 4.3 (For reference only, please check.) |
14.4 Packing group, if applicable
| ADR/RID: III (For reference only, please check.) | IMDG: III (For reference only, please check.) | IATA: III (For reference only, please check.) |
14.5 Environmental hazards
| ADR/RID: Yes | IMDG: Yes | IATA: Yes |
14.6 Special precautions for user
no data available
14.7 Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations specific for the product in question
| Chemical name | Common names and synonyms | CAS number | EC number |
|---|---|---|---|
| Maneb | Maneb | 12427-38-2 | 235-654-8 |
| European Inventory of Existing Commercial Chemical Substances (EINECS) | Listed. | ||
| EC Inventory | Listed. | ||
| United States Toxic Substances Control Act (TSCA) Inventory | Not Listed. | ||
| China Catalog of Hazardous chemicals 2015 | Listed. | ||
| New Zealand Inventory of Chemicals (NZIoC) | Listed. | ||
| Philippines Inventory of Chemicals and Chemical Substances (PICCS) | Listed. | ||
| Vietnam National Chemical Inventory | Listed. | ||
| Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) | Listed. | ||
| Korea Existing Chemicals List (KECL) | Listed. | ||
SECTION 16: Other information
Information on revision
| Creation Date | July 15, 2019 |
|---|---|
| Revision Date | July 15, 2019 |
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
UN number 2968: Haz class 4.3; Pack Group III; Maneb stabilized against self-heating.Carrier solvents used in commercial formulations may change physical and toxicological properties.
Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.
Industry News
More Safety Data Sheets