The latest development of PROTAC worldwide
Focus on the most cutting-edge research results in the field of protein degradation and catch the latest developments in the PROTAC market? It's all in the five-minute "Today's PROTAC Headlines" series of tweets from Minox's ReThinking PROTAC platform.
Recently, Kymera Therapeutics Publishes Recent Patent for SMARCA degrader (WO 2022/125804 A1), Ram Sabnis (Smith, Gambrell & Russell LLP, "The patent was refined and briefly analyzed in ACS Medicinal Chemistry."
1, represents the molecule
2. Targets and indications
Target: Switch/Sucrose Non-Fermentable (SWI/SNF)-Related, Matrix-Associated, Actin-Dependent Regulator of Chromatin, Subfamily A (SMARCA), including SMARCA2, SMARCA4, PB1, etc.
◆ Indications: Cancer
3. Synthetic pathways
4. Biological activity
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