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Home > News > Blog > What Are The Uses Of Maslinic Acid In Skin Care?

What Are The Uses Of Maslinic Acid In Skin Care?

ECHEMI 2022-03-09

Maslinic acid in skin care has many uses because it has anti-inflammatory, antioxidant, and antimicrobial properties relevant when considering its application in topical formulations.

Maslinic acid was identified in the common olive Olea europaea (Oleaceae). The fruit of this plant contains about 5% oleuropein complex (OEC), which is a mixture of ligstroside aglycone and hydroxytyrosol. The hydroxytyrosol is transformed in the maturation process, giving rise to maslinic acid, the concentration of which can reach 0.2%. Since this discovery, many studies have been conducted on maslinic acid for its biological activities, which has led to the current interest in maslinic acid by the cosmetic and pharmaceutical industries.

 Maslinic Acid in Skin Care

 Maslinic acid in Skin Care: A Review of Anti-Inflammatory, Antioxidant and Antimicrobial Properties *

 Anti-inflammatory Properties

 Maslinic acid can be considered an anti-inflammatory agent because it suppresses the production of prostaglandin E2 (PGE2), which is involved in triggering skin inflammation. PGE2 levels increase during inflammation and attract immune system cells, resulting in swelling, redness, and itching. Apart from inhibiting PGE2 production, maslinic acid also reduces the expression of COX-2.

 COX enzymes are involved in converting arachidonic acid into PGE2 and more than two dozen other fatty acids. The COX enzymes have been divided into two major subgroups: COX-1 and COX-2, which have different functions and can be affected by various substances.

 COX-1 is expressed constitutively in most tissues, while COX-2 expression usually is low. Still, it can increase as a response to certain stimuli, such as the presence of bacteria or viruses, trauma, or exposure to environmental carcinogens.

 Inhibition of both isoforms allows inhibiting the production of several prostaglandins at once, which reduces the likelihood that bacteria or viruses will become resistant to these anti-inflammatory drugs. Although COX-2 inhibitors have been approved for use in humans and are being investigated as agents to prevent colon cancer, a recent study demonstrated that a single dose of aspirin could interfere with converting arachidonic acid into PGE2 and reduce COX-2 levels. According to other studies, 125 mg of maslinic acid has the same effect as aspirin because it reduces COX-2 production by 50-60%.

 Antioxidant Properties:

 Maslinic acid is an antioxidant compound, and its antioxidant activity is comparable to the synthetic antioxidant butylated hydroxyanisole (BHA). Maslinic acid can scavenge free radicals and increase the total phenolic compounds present in an aqueous extract of olive leaves, thus indicating that maslinic acid may contribute to the potential antioxidant activity of olive leaf extracts.

 Antimicrobial Properties

 The antimicrobial activity of maslinic acid was demonstrated against two Gram-positive bacteria, namely Staphylococcus aureus, and Bacillus subtilis, which are responsible for skin infections in immunocompromised patients. Maslinic acid may also act as an effective antimicrobial agent against pathogenic bacteria such as "Pseudomonas aeruginosa."

 In addition to these properties, maslinic acid has been identified as a potent phytoestrogen, and it can modulate the expression of genes involved in cell division, differentiation, and apoptosis. Maslinic acid also exerts a protective effect on human skin cells against reactive oxygen species (ROS), and it can counteract the expression of some ROS-producing enzymes.

Why Use Maslinic Acid for your Face?

 It helps fight acne and other skin conditions

 Maslinic acid also has anti-inflammatory properties that can help reduce the redness and irritation caused by acne. A study on human sebocytes found that maslinic acid inhibits lipid synthesis of these cells at concentrations as low as 0.1 M. The researchers wrote: "The inhibition of lipid synthesis was

 Ensures you have a glowing face

 Maslinic acid effectively rejuvenates tired skin and removes dead skin cells from the inside out. It reduces the signs of fatigue by combating stress on a cellular level. According to researchers, maslinic acid "stimulates glycolysis in human keratinocytes without affecting cell proliferation," meaning that it promotes new production.

 Prevents Skin Infections

 Maslinic acid has antimicrobial properties helpful in treating skin infections like acne, dermatitis, and eczema. This organic compound can fight acne by inhibiting the growth of bacteria on the surface of your skin. It also reduces inflammation; this helps decrease redness and irritation caused by acne.

 Conclusion

 Maslinic acid in skincare is very beneficial to the skin because it has antibacterial, anti-inflammatory, and antioxidant properties that help keep your face clear of acne, free from irritation, and protect against environmental toxins.

Disclaimer: ECHEMI reserves the right of final explanation and revision for all the information.

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