Progress In Vaccine For Diabetes Mellitus Research

Although diabetes is a chronic disease, its incurable and controllable mode still confuses the public and the medical community. Moreover, taking medication frequently every day also makes it difficult for many patients to adapt. It would be great if there was a vaccine for diabetes mellitus that could control blood sugar in a short period of time through injections without having to take medicine every day. And the medical community has been pushing for such research.

Oral vaccine for diabetes

"Diabetes Oral Vaccine" is extracted from pure natural plants, and the main ingredients are bitter gourd, American ginseng and astragalus. A large number of clinical experiments have proved that: "Diabetes Oral Vaccine" capsules can restore islet beta cell function index, restore insulin secretion, and can be taken with any drug at the same time. And no drug resistance and dependence, no toxic side effects. Stop taking chemical hypoglycemic drugs, blood sugar remains stable. In this way, we can get rid of the dependence on chemical hypoglycemic drugs to the greatest extent, and enjoy normal work and life like healthy people. As a biological preparation, "diabetic oral vaccine" can achieve self-regulation of insulin secretion by increasing the viability of islet cells. Therefore, the primary requirement is that the islet cells of diabetic patients have the ability to be repaired and activated. On the contrary, if the islet cells have been severely damaged or exhausted, it is difficult to achieve the purpose of improving their vitality.

Mechanism of action

Using local release technology of nitric oxide and high-tech enzymatic hydrolysis technology to artificially synthesize active polypeptide protease from natural plants, bitter gourd, American ginseng, and astragalus, and with the cooperation of trivalent chromium, it overcomes the technological bottleneck of short life cycle of active polypeptide protease. This research result will provide a new treatment approach for diabetic patients from the field of islet cell immunity, which is safe and has no toxic side effects. "Diabetes Oral Vaccine" repairs islet cells, improves islet cell disease resistance, and stimulates islet cell viability. At the same time, it contains polypeptide active protease, which can improve islet receptor activity, thereby correcting insulin resistance, improving insulin sensitivity, and then improve insulin resistance and durability. When glucose metabolism returns to normal function, it can not only prevent the occurrence and development of complications, but also promote lipid metabolism, reduce fatty liver, reduce the burden of islet cells and prevent their failure.

New vaccine for diabetes mellitus

In 2019, the Chinese scientific community has successfully developed a vaccine for the treatment of type 1 diabetes, which was developed by the team of Xi Yongzhi, director of the Immunology Department of the Fifth Medical Center of the PLA General Hospital. DNA vaccine based on B7-1-PE40KDEL exotoxin fusion gene, in previous animal experiments, the vaccine can treat type 1 diabetes, correct the patient's own disordered cells and humoral immune responses, repair damaged islet beta cells, and restore itself secretion of insulin. The most important thing is that this drug only needs to be injected once a month to maintain the effect for a month, so as to avoid the trouble of daily medication for diabetic patients. At present, the drug has been applied for clinical trials. This achievement is an original achievement with completely independent intellectual property rights, and it is also the first international "triple-party" invention patent authorization obtained in the field of new therapeutic DNA vaccines. This achievement represents an important breakthrough in the research field of new biological treatment drugs for type 1 diabetes in China, and also marks that China is at the forefront of the world in innovative research on a new type of therapeutic vaccine for diabetes mellitus.

Summary

With the development of modern medical technology, vaccine for diabetes mellitus has been developed, and it is believed that with continuous improvement, it will soon be put into use. It may be in the near future that a specific drug can be developed for the treatment of diabetes, and it is possible to be cured. No matter what a diabetic patient eats, the most important thing is to control the total intake and adjust the diet reasonably so that the blood sugar can be maintained at a normal level. In short, the application of pharmaceutical science, reasonable intake of diet, correct adjustment of exercise, and good medication and living habits of diabetic patients can maintain the body at a normal level.