Guangdong Huanan Pharmaceutical Group Co., Ltd.

It inhibits the synthesis and release of prostaglandins in the hypothalamus, restores the normal responsiveness of the sensory neurons in the temperature regulation center, and has an antipyretic effect; it has an analgesic effect by inhibiting the synthesis of prostaglandins, etc.; it inhibits the synthesis and release of prostaglandins in the local tissue of inflammation, stabilizes lysosomal enzymes, and affects the phagocytic function of phagocytes, thus having an anti-inflammatory effect

It is a peripheral analgesic. It inhibits the synthesis and release of prostaglandins (PGE1) in the hypothalamic temperature regulation center, causing peripheral vasodilation and sweating to achieve an antipyretic effect; it can also inhibit the effects of PGE1, bradykinin and histamine, increase the pain threshold and produce analgesic effects.

It is a central nervous system stimulant that can excite the cerebral cortex, increase sensitivity to the outside world, and constrict cerebral blood vessels, thus enhancing the headache relief effects of the first two drugs.

It has a strong histamine H1 receptor blocking effect, can alleviate other respiratory symptoms caused by allergies, and also has a mild inhibitory effect on the central nervous system

It has a strong antibacterial effect on most anaerobic bacteria, and its bactericidal mechanism has not yet been fully elucidated. The nitroreductase of anaerobic bacteria plays an important role in the energy metabolism of sensitive strains. The nitro group of this product is reduced to a cytotoxin, thereby acting on the DNA metabolism process of bacteria and promoting cell death.

It is a long-acting nonsteroidal anti-inflammatory analgesic. After entering the body, it is metabolized into diphenyl ethyl ester, which can inhibit the activity of cyclooxygenase, reduce the synthesis of prostaglandins, and produce anti-inflammatory, analgesic and antipyretic effects.

This product is a blood lipid regulating drug of clofibric acid derivatives. It reduces blood low-density lipoprotein, cholesterol and triglycerides by inhibiting the production of very low-density lipoprotein and triglycerides and increasing their catabolism at the same time; it also increases the production of apolipoprotein A1 and A11, thereby increasing high-density lipoprotein. This product also has the effect of reducing blood uric acid in normal people and patients with hyperuricemia.

This product has anti-inflammatory, antipyretic and analgesic effects. Its mechanism of action is to reduce the synthesis of prostaglandins by inhibiting cyclooxygenase. It stops the formation of pain nerve impulses in inflammatory tissues and inhibits inflammatory reactions, including inhibiting the chemotaxis of leukocytes and the release of lysosomal enzymes. As for the antipyretic effect, it acts on the hypothalamic temperature regulation center, causing peripheral vasodilation and sweating, which increases heat dissipation. This central antipyretic effect may also be related to the inhibition of prostaglandin synthesis in the hypothalamus.

This product is a synthetic antibacterial anti-tuberculosis drug that can penetrate into mycobacteria to interfere with RNA synthesis, thereby inhibiting bacterial reproduction. It is only effective against mycobacteria in the growth and reproduction period. So far, no cross-resistance has been found between this product and other anti-tuberculosis drugs.