Jiangsu Kanion Pharmaceutical Co., Ltd.
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Founded in:
1996-05-08 -
Country:
China -
Address:
Lianyungang Economic and Technological Development Zone Jiangning Industrial City -
Tax NO.:
91320700138997640W -
Registered Funds:
581.797452 million yuan -
Website:
-
Email:
| Name | Description | Content | CAS NO. | Registered Holders |
|---|---|---|---|---|
| Ginkgo diterpene lactone |
No specific pharmacological information is provided
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No specific pharmacological information is provided |
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| Name | Description | Content | CAS NO. | Registered Holders |
|---|---|---|---|---|
| Ginkgolide A |
|
15291-75-5 | 0 | |
| Ginkgolide B |
|
15291-77-7 | 0 | |
| Ginkgolide K |
|
153355-70-5 | 0 |
| Name | Description | Content | CAS NO. | Registered Holders |
|---|---|---|---|---|
| Rhodiola rosea |
No specific pharmacological effects mentioned
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No specific pharmacological effects mentioned |
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| Name | Description | Content | CAS NO. | Registered Holders |
|---|---|---|---|---|
| Rhodiola rosea |
Preclinical animal experiments show that this product can enhance myocardial contractility, improve cardiac hemodynamics, improve epicardial ischemic electrocardiogram, and reduce myocardial cell acidosis; reduce coronary resistance, reduce myocardial oxygen consumption and oxygen consumption index, reduce blood pressure, slow heart rate; prolong the disappearance time of mouse electrocardiogram after tracheal clamping; prolong the survival time of mice under normal pressure and low pressure hypoxia tolerance; inhibit platelet aggregation, reduce in vitro thrombosis; improve ischemic changes in electrocardiogram caused by intravenous injection of posterior pituitary hormone; increase fasting blood glucose level in rats. In the acute toxicity test, mice were given a single oral administration of 58.8g crude drug/kg (equivalent to 223 times the clinical daily dose), and no toxic reaction was observed for 7 consecutive days; in the long-term toxicity test, rats were given oral administration of 2g crude drug/kg, 4g crude drug/kg, and 8g crude drug/kg (equivalent to 30 times, 60 times, and 120 times the clinical daily dose), and there was no obvious toxic effect for 12 consecutive weeks.
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Preclinical animal experiments show that this product can enhance myocardial contractility, improve cardiac hemodynamics, improve epicardial ischemic electrocardiogram, and reduce myocardial cell acidosis; reduce coronary resistance, reduce myocardial oxygen consumption and oxygen consumption index, reduce blood pressure, slow heart rate; prolong the disappearance time of mouse electrocardiogram after tracheal clamping; prolong the survival time of mice under normal pressure and low pressure hypoxia tolerance; inhibit platelet aggregation, reduce in vitro thrombosis; improve ischemic changes in electrocardiogram caused by intravenous injection of posterior pituitary hormone; increase fasting blood glucose level in rats. In the acute toxicity test, mice were given a single oral administration of 58.8g crude drug/kg (equivalent to 223 times the clinical daily dose), and no toxic reaction was observed for 7 consecutive days; in the long-term toxicity test, rats were given oral administration of 2g crude drug/kg, 4g crude drug/kg, and 8g crude drug/kg (equivalent to 30 times, 60 times, and 120 times the clinical daily dose), and there was no obvious toxic effect for 12 consecutive weeks. |
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| Name | Description | Content | CAS NO. | Registered Holders |
|---|---|---|---|---|
| Dracaena |
Increase the pain threshold of mice, inhibit inflammatory response, improve microcirculation, and inhibit endometrial growth
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Increase the pain threshold of mice, inhibit inflammatory response, improve microcirculation, and inhibit endometrial growth |
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| NOTOGINSENG RADIX ET RHIZOMA |
Increase pain threshold of mice, inhibit inflammatory response, improve microcirculation, and regulate hormone levels
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Increase pain threshold of mice, inhibit inflammatory response, improve microcirculation, and regulate hormone levels |
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| FRITILLARIAE THUNBERGII BULBUS |
Inhibit inflammatory response, regulate hormone levels, and improve immune function
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Inhibit inflammatory response, regulate hormone levels, and improve immune function |
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| COICIS SEMEN |
Inhibit inflammatory response, improve microcirculation, and enhance immune function
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Inhibit inflammatory response, improve microcirculation, and enhance immune function |
0 |