Animal experiments have shown that it has antihypertensive and diuretic effects on experimental hypertensive animals. This effect is related to the dose: it shows a hypotensive effect at low doses and a diuretic effect at high doses. Its hypotensive mechanism may be to act on the walls of small arteries, reduce vascular tension and vascular responsiveness to pressor substances, thereby reducing peripheral vascular resistance; it may also be related to the diuretic effect. Within the therapeutic dose range, in addition to hypotensive and diuretic effects, it has no obvious effect on the nervous system, respiratory system, digestive system and blood system.

It has anti-cerebral ischemia effect, improves brain edema in rats with multiple cerebral infarction, promotes glial cell reaction of brain softening foci, accelerates the absorption and organization of softening foci, and reduces neuronal lesions in the hippocampus; it has a protective effect on delayed neuronal damage in the hippocampus of gerbils with transient cerebral ischemia, can reduce the Ca2+ content in brain tissue after ischemia, reduce the number of dead neurons, and increase neuronal density. It has anti-myocardial ischemia effect, can reduce the downward shift of the S-T segment of the electrocardiogram caused by acute myocardial ischemia in rats, and adjust the heterogeneity of the electrocardiogram. It improves blood rheology, reduces whole blood viscosity and plasma viscosity, reduces hematocrit and platelet aggregation rate, slows down erythrocyte sedimentation rate, and reduces fibrinogen content. It improves microcirculation, reduces the morphological integral, flow integral, semi-circular integral, and overall integral of the nail fold microcirculation, reduces peri-loop exudation, increases flow velocity, reduces red blood cell aggregation, reduces loop top congestion, increases loop clarity, and subsides edema. It has the effect of lowering blood lipids, reducing total cholesterol, triglycerides, serum triglycerides, cholesterol and low-density lipoprotein levels. It has the effect of resisting free radical damage, increasing the activity of superoxide dismutase in erythrocytes, reducing the content of malondialdehyde in plasma, and reducing the content of serum protein kinase C and aspartate aminotransferase.