This product is a H2 receptor blocker of the guanyl thiazole class, which has the characteristics of high affinity for H2 receptors, and has a significant inhibitory effect on gastric acid secretion, and has an inhibitory effect on basal secretion and the increase of gastric acid and pepsin caused by various stimuli. This product does not change the gastric emptying rate, does not interfere with pancreatic function, and has no adverse effects on the cardiovascular system and kidney function. This product is different from cimetidine, but it is similar to ranitidine, that is, long-term high-dose treatment does not cause adverse reactions of androgen antagonism such as male breast development, impotence, lack of sexual desire, and female breast pain, galactorrhea, etc. It has no teratogenic, carcinogenic, drug enzyme inhibitory and androgen inhibitory effects.

It is a highly selective 5-HT3 receptor antagonist, which has a good preventive and therapeutic effect on nausea and vomiting caused by radiotherapy, chemotherapy and surgery. It inhibits the occurrence of nausea and vomiting by antagonizing the 5-HT3 receptors in the central chemoreceptor area and peripheral vagus nerve endings. This product has high selectivity and no adverse reactions such as extrapyramidal reactions and excessive sedation.

It has an antipyretic effect on fever in rats caused by 2,4-nitrophenol and Escherichia coli, and fever in rabbits caused by triple vaccine; it can prolong the average survival time of mice infected with influenza virus, and has a certain reducing effect on the lung index of mice infected with influenza virus; it has a certain reducing effect on the mortality of mice infected with Staphylococcus aureus and Klebsiella pneumoniae; it can inhibit the ear swelling of mice caused by xylene; it can increase the serum carbon clearance index of mice, increase the serum hemolysin level, and enhance the delayed-type hypersensitivity reaction of mice induced by sheep red blood cells; it can inhibit the writhing pain reaction of mice caused by acetic acid.

It has an antipyretic effect on fever in rats caused by 2,4-nitrophenol and Escherichia coli, and fever in rabbits caused by triple vaccine; it can prolong the average survival time of mice infected with influenza virus, and has a certain reducing effect on the lung index of mice infected with influenza virus; it has a certain reducing effect on the mortality of mice infected with Staphylococcus aureus and Klebsiella pneumoniae; it can inhibit the ear swelling of mice caused by xylene; it can increase the serum carbon clearance index of mice, increase the serum hemolysin level, and enhance the delayed-type hypersensitivity reaction of mice induced by sheep red blood cells; it can inhibit the writhing pain reaction of mice caused by acetic acid.

It has an antipyretic effect on fever in rats caused by 2,4-nitrophenol and Escherichia coli, and fever in rabbits caused by triple vaccine; it can prolong the average survival time of mice infected with influenza virus, and has a certain reducing effect on the lung index of mice infected with influenza virus; it has a certain reducing effect on the mortality of mice infected with Staphylococcus aureus and Klebsiella pneumoniae; it can inhibit the ear swelling of mice caused by xylene; it can increase the serum carbon clearance index of mice, increase the serum hemolysin level, and enhance the delayed-type hypersensitivity reaction of mice induced by sheep red blood cells; it can inhibit the writhing pain reaction of mice caused by acetic acid.

This product is a bone metabolism regulator, an aminobisphosphonate, which has a strong affinity with hydroxyapatite in the bone. It can enter the hydroxyapatite crystals in the bone matrix. When osteoclasts dissolve the crystals, the drug is released, which can inhibit the activity of osteoclasts and indirectly inhibit bone resorption through osteoblasts. It is characterized by strong anti-bone resorption activity and no bone mineralization inhibition.