Yangtze River Pharmaceutical (Group) Co., Ltd.

This product is a synthetic tropic acid derivative with four ammonium structures. It is a parasympathetic nerve blocker with similar effects to atropine. It mainly works by competitively binding with the endogenous neurotransmitter acetylcholine to the postsynaptic membrane M-receptor. It reduces the tension of the parasympathetic nerves and removes the smooth muscle spasms caused by the parasympathetic nerves in the organs controlled by the parasympathetic nerves. It also has a certain effect on the gastrointestinal tract, bile duct and urinary tract. This product has low fat solubility and is not easy to pass through the blood-brain barrier, and will not produce side effects on the central nervous system.

This product is a commonly used contrast agent for X-ray and CT examinations, and can be used in blood vessels, spinal canals, and body cavities. Animal test results show that this product has an enhancement effect on dog liver, abdominal aorta, and CT scan images.

Nucleoside antiviral drugs. After entering the cell, this product is rapidly phosphorylated to a monophosphate compound, and then becomes a triphosphate compound through the action of cellular kinase. Its phosphorylation in cells infected with cytomegalovirus is faster than that in normal cells. Ganciclovir can competitively inhibit DNA polymerase and incorporate into the DNA of viruses and host cells, thereby inhibiting DNA synthesis. This product has a stronger inhibitory effect on viral DNA polymerase than host cell polymerase. In animal experiments, this product has teratogenic, carcinogenic, immunosuppressive effects and reproductive system toxicity.