Hubei Changlian Dule Pharmaceutical Co., Ltd. | Pharmaceutical Manufacturer Profile & Drug Portfolio Page 7

Compound Amino Acid Injection (18AA)

The main ingredients of this product are: 18 kinds of amino acids. The amino acid content is 10%. Amino acid concentration (mg/1000ml) L-isoleucine 560 L-arginine 790 L-leucine 1,250 L-aspartic acid 380 acetate L-lysine 1,240 L-cysteine 100 (equivalent to lysine 880) L-glutamic acid 650 L-methionine 350 L-histidine 600 L-phenylalanine 935 L-proline 330 L-threonine 650 L-serine 220 L-tryptophan

Name	Description	Content	CAS NO.	Registered Holders
L-Isoleucine	Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions More Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions	560mg/1000 ml	73-32-5	19
L(+)-Arginine	Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions More Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions	790mg/1000 ml	74-79-3	25
L-Leucine	Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions More Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions	1250mg/1000 ml	61-90-5	10
L-Aspartic acid	Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions More Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions	380mg/1000 ml	56-84-8	1
L-Lysine Acetate Salt	Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions More Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions	1240mg/1000 ml	57282-49-2	13
L-Cysteine	Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions More Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions	100mg/1000 ml	52-90-4	6
L-Glutamic acid	Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions More Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions	650mg/1000 ml	56-86-0	17
L-Methionine	Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions More Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions	350mg/1000 ml	63-68-3	12
L-Histidine	Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions More Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions	600mg/1000 ml	71-00-1	20
L-Phenylalanine	Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions More Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions	935mg/1000 ml	3617-44-5	0
L-Proline	Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions More Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions	330mg/1000 ml	147-85-3	13
L-Threonine	Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions More Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions	650mg/1000 ml	72-19-5	13
L-Serine	Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions More Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions	220mg/1000 ml	56-45-1	9
L-Tryptophan	Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions More Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions		73-22-3	12

Compound Amino Acid Injection (9AA)

This product is a compound preparation, made up of 9 kinds of amino acids. Its components are as follows: L-histidine (C6H9N3O2) 2.5g L-isoleucine (C6H13NO2) 5.6g L-leucine (C6H13NO2) 8.8g L-lysine acetate (C6H14N2O2·C2H4O2) 9.0g L-methionine (C15H11NO2S) 8.8g L-phenylalanine (C9H11N

Name	Description	Content	CAS NO.	Registered Holders
L-Histidine	Supplement essential amino acids in the body and improve nutritional status; restore the decreased plasma concentration of essential amino acids; enhance assimilation and reduce protein decomposition and utilization; alleviate symptoms of uremia; lower blood phosphorus and correct calcium-phosphorus metabolism disorders. More Supplement essential amino acids in the body and improve nutritional status; restore the decreased plasma concentration of essential amino acids; enhance assimilation and reduce protein decomposition and utilization; alleviate symptoms of uremia; lower blood phosphorus and correct calcium-phosphorus metabolism disorders.	2.5g	71-00-1	20
L-Isoleucine	Supplement essential amino acids in the body and improve nutritional status; restore the decreased plasma concentration of essential amino acids; enhance assimilation and reduce protein decomposition and utilization; alleviate symptoms of uremia; lower blood phosphorus and correct calcium-phosphorus metabolism disorders. More Supplement essential amino acids in the body and improve nutritional status; restore the decreased plasma concentration of essential amino acids; enhance assimilation and reduce protein decomposition and utilization; alleviate symptoms of uremia; lower blood phosphorus and correct calcium-phosphorus metabolism disorders.	5.6g	73-32-5	19
L-Leucine	Supplement essential amino acids in the body and improve nutritional status; restore the decreased plasma concentration of essential amino acids; enhance assimilation and reduce protein decomposition and utilization; alleviate symptoms of uremia; lower blood phosphorus and correct calcium-phosphorus metabolism disorders. More Supplement essential amino acids in the body and improve nutritional status; restore the decreased plasma concentration of essential amino acids; enhance assimilation and reduce protein decomposition and utilization; alleviate symptoms of uremia; lower blood phosphorus and correct calcium-phosphorus metabolism disorders.	8.8g	61-90-5	10
L-Lysine Acetate Salt	Supplement essential amino acids in the body and improve nutritional status; restore the decreased plasma concentration of essential amino acids; enhance assimilation and reduce protein decomposition and utilization; alleviate symptoms of uremia; lower blood phosphorus and correct calcium-phosphorus metabolism disorders. More Supplement essential amino acids in the body and improve nutritional status; restore the decreased plasma concentration of essential amino acids; enhance assimilation and reduce protein decomposition and utilization; alleviate symptoms of uremia; lower blood phosphorus and correct calcium-phosphorus metabolism disorders.	9.0g	52315-92-1	0
L-Methionine	Supplement essential amino acids in the body and improve nutritional status; restore the decreased plasma concentration of essential amino acids; enhance assimilation and reduce protein decomposition and utilization; alleviate symptoms of uremia; lower blood phosphorus and correct calcium-phosphorus metabolism disorders. More Supplement essential amino acids in the body and improve nutritional status; restore the decreased plasma concentration of essential amino acids; enhance assimilation and reduce protein decomposition and utilization; alleviate symptoms of uremia; lower blood phosphorus and correct calcium-phosphorus metabolism disorders.	8.8g	63-68-3	12
L-Phenylalanine	Supplement essential amino acids in the body and improve nutritional status; restore the decreased plasma concentration of essential amino acids; enhance assimilation and reduce protein decomposition and utilization; alleviate symptoms of uremia; lower blood phosphorus and correct calcium-phosphorus metabolism disorders. More Supplement essential amino acids in the body and improve nutritional status; restore the decreased plasma concentration of essential amino acids; enhance assimilation and reduce protein decomposition and utilization; alleviate symptoms of uremia; lower blood phosphorus and correct calcium-phosphorus metabolism disorders.		3617-44-5	0

Fat emulsion injection (C14～24)

Its structural formula is: CH2OCOR1R2COOCHOCH2-O-P-O-CH2CH2N(CH3)O This product is a sterile emulsion made of injectable soybean oil emulsified with injectable lecithin and adding injectable glycerin. Each 1000ml contains: 10% 20% 30% injectable soybean oil 100g 200g 300g injectable lecithin 12g 12g 12g injectable glycerin 22g 22g 16.7g injectable water (added to) 1000m1 1000m1 1000m1 pH value is about 888 Osmotic pressure/kgH2O) 300 35O310 Energy MJ (kcal) 4.6 (1100) 8.4 (2000) 12.6 (3000).

Name	Description	Content	CAS NO.	Registered Holders
Soybean oil	It provides essential fatty acids, which serve as the body's main energy source. After oxidation, it releases energy for the body to use. It is a precursor of physiologically active substances such as prostaglandins, thromboxanes and leukotrienes. More It provides essential fatty acids, which serve as the body's main energy source. After oxidation, it releases energy for the body to use. It is a precursor of physiologically active substances such as prostaglandins, thromboxanes and leukotrienes.	100g/200g/300gg	8001-22-7	24
Egg phospholipids	It constitutes the basic skeleton of the lipid bilayer of cell biological membrane, participates in the transport of fat and cholesterol, has the effect of resisting hypercholesterolemia, and facilitates the dissolution and excretion of cholesterol. More It constitutes the basic skeleton of the lipid bilayer of cell biological membrane, participates in the transport of fat and cholesterol, has the effect of resisting hypercholesterolemia, and facilitates the dissolution and excretion of cholesterol.	12gg	93685-90-6	25
Glycerol	Certain unsaturated fatty acids cannot be synthesized by the body itself and must be taken from vegetable oils. They are indispensable nutrients for the body, so they are called essential fatty acids. They are also the precursors of physiologically active substances such as prostaglandins, thromboxanes and leukotrienes. Fatty acids are the main energy source for the human body, and fatty acid oxidation is an important source of energy in the body. When the oxygen supply is sufficient, fatty acids can be decomposed into CO2 and H2O in the body and release a large amount of energy, which is used by the body in the form of ATP. Except for brain tissue, most tissues can oxidize fatty acids, especially liver and muscles. Phospholipids are the basic skeleton of the lipid bilayer of cell biological membranes (cell membranes, nuclear membranes, mitochondrial membranes), and they also constitute various lipoproteins. It is the main component of bile and participates in the transportation of fat and cholesterol. If the phospholipids in plasma are too low, the cholesterol/lecithin ratio will increase, and cholesterol deposition will easily occur, causing atherosclerosis, so phospholipids have an effect on resisting hypercholesterolemia. In addition, in bile, phospholipids form colloids together with bile salts and cholesterol, which is beneficial to the dissolution and excretion of cholesterol. Lecithin is widely distributed in nature. It is relatively abundant in seeds such as soybeans in plants, and has the highest content in nerve tissue in animals. This product is a sterilized fat emulsion for intravenous infusion, containing soybean oil for injection and lecithin for injection, of which about 60% of fatty acids are essential fatty acids. The particle size and biological properties of this product are similar to those of natural chylomicrons. More Certain unsaturated fatty acids cannot be synthesized by the body itself and must be taken from vegetable oils. They are indispensable nutrients for the body, so they are called essential fatty acids. They are also the precursors of physiologically active substances such as prostaglandins, thromboxanes and leukotrienes. Fatty acids are the main energy source for the human body, and fatty acid oxidation is an important source of energy in the body. When the oxygen supply is sufficient, fatty acids can be decomposed into CO2 and H2O in the body and release a large amount of energy, which is used by the body in the form of ATP. Except for brain tissue, most tissues can oxidize fatty acids, especially liver and muscles. Phospholipids are the basic skeleton of the lipid bilayer of cell biological membranes (cell membranes, nuclear membranes, mitochondrial membranes), and they also constitute various lipoproteins. It is the main component of bile and participates in the transportation of fat and cholesterol. If the phospholipids in plasma are too low, the cholesterol/lecithin ratio will increase, and cholesterol deposition will easily occur, causing atherosclerosis, so phospholipids have an effect on resisting hypercholesterolemia. In addition, in bile, phospholipids form colloids together with bile salts and cholesterol, which is beneficial to the dissolution and excretion of cholesterol. Lecithin is widely distributed in nature. It is relatively abundant in seeds such as soybeans in plants, and has the highest content in nerve tissue in animals. This product is a sterilized fat emulsion for intravenous infusion, containing soybean oil for injection and lecithin for injection, of which about 60% of fatty acids are essential fatty acids. The particle size and biological properties of this product are similar to those of natural chylomicrons.	22g/22g/16.7gg	56-81-5	61

Compound Amino Acid Injection (18AA)

The main ingredients of this product are: 18 kinds of amino acids. The amino acid content is 10%. Amino acid concentration (mg/1000ml) L-isoleucine 560 L-arginine 790 L-leucine 1,250 L-aspartic acid 380 acetate L-lysine 1,240 L-cysteine 100 (equivalent to lysine 880) L-glutamic acid 650 L-methionine 350 L-histidine 600 L-phenylalanine 935 L-proline 330 L-threonine 650 L-serine 220 L-tryptophan

Name	Description	Content	CAS NO.	Registered Holders
L-Isoleucine	Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions More Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions	560mg/1000 ml	73-32-5	19
L(+)-Arginine	Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions More Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions	790mg/1000 ml	74-79-3	25
L-Leucine	Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions More Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions	1250mg/1000 ml	61-90-5	10
L-Aspartic acid	Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions More Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions	380mg/1000 ml	56-84-8	1
L-Lysine Acetate Salt	Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions More Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions	1240mg/1000 ml	57282-49-2	13
L-Cysteine	Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions More Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions	100mg/1000 ml	52-90-4	6
L-Glutamic acid	Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions More Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions	650mg/1000 ml	56-86-0	17
L-Methionine	Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions More Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions	350mg/1000 ml	63-68-3	12
L-Histidine	Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions More Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions	600mg/1000 ml	71-00-1	20
L-Phenylalanine	Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions More Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions	935mg/1000 ml	3617-44-5	0
L-Proline	Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions More Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions	330mg/1000 ml	147-85-3	13
L-Threonine	Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions More Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions	650mg/1000 ml	72-19-5	13
L-Serine	Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions More Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions	220mg/1000 ml	56-45-1	9
L-Tryptophan	Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions More Participate in protein anabolism, obtain positive nitrogen balance, and generate enzymes, hormones, antibodies, structural proteins, promote tissue healing, and restore normal physiological functions		73-22-3	12

Curcuma Oil and Glucose Injection

The main ingredient of this product is zedoary oil.

Name	Description	Content	CAS NO.	Registered Holders
Curcuma oil	It has a direct inhibitory effect on respiratory syncytial virus (RSV) and a direct inactivation effect on influenza virus A1 and A3. It has no local irritation and hemolysis in vivo. The LD50 of intravenous injection in mice is 122.14±41.44mg/kg; the LD50 of oral gavage in mice is 147.0g/kg; the LD50 of intramuscular injection is 55g/kg; the maximum tolerance and minimum lethal dose in mice are 48 and 49g/kg respectively. No accumulation effect is observed after six consecutive days of medication. More It has a direct inhibitory effect on respiratory syncytial virus (RSV) and a direct inactivation effect on influenza virus A1 and A3. It has no local irritation and hemolysis in vivo. The LD50 of intravenous injection in mice is 122.14±41.44mg/kg; the LD50 of oral gavage in mice is 147.0g/kg; the LD50 of intramuscular injection is 55g/kg; the maximum tolerance and minimum lethal dose in mice are 48 and 49g/kg respectively. No accumulation effect is observed after six consecutive days of medication.		8024-37-1	1