It is a fat-soluble quinone compound widely present in organisms. It plays an important role in proton translocation and electron transfer in the human respiratory chain. It can be used as an activator of cell metabolism and cell respiration. It is also an important antioxidant and nonspecific immunopotentiator. It has the functions of promoting oxidative phosphorylation reaction and protecting the structural integrity of biological membranes. It has the following effects: 1. Anti-myocardial ischemia effect: It can reduce the weakening of myocardial contractility and the reduction of creatine phosphate and adenosine triphosphate during acute ischemia, help maintain the morphological structure of mitochondria in ischemic myocardial cells, and reduce the scope of experimental myocardial infarction, which has a certain protective effect on ischemic myocardium. 2. Increase cardiac output, reduce peripheral resistance, help to resist heart failure, inhibit the synthesis and secretion of aldosterone and interfere with its effect on renal tubules. 3. Anti-arrhythmic effect: When perfusing isolated animal ventricular muscles under hypoxic conditions, it can shorten the duration of action potential. The threshold for ventricular arrhythmia measured by electrical stimulation is lower than that of the control group. After the coronary artery is opened, the threshold recovery is also faster. 4. Reduce peripheral vascular resistance. In addition, it has the effects of resisting the cardiotoxicity of doxorubicin and protecting the liver. About 75% of patients with coronary heart disease can relieve symptoms such as angina pectoris, chest tightness, palpitations, and dyspnea after taking the drug, and the electrocardiogram can be improved. It is helpful in treating ventricular premature beats. In addition, it can be used as an auxiliary treatment for a variety of diseases.

It has the effects of reducing swelling, anti-inflammatory and improving blood circulation

It has the effects of reducing swelling, anti-inflammatory and improving blood circulation

This product is a potassium sodium salt of dehydrated andrographolide succinate half ester made by esterification, dehydration and salt formation of andrographolide, which is the same substance as the active metabolite of Andrographolide in the body. It has antipyretic, anti-inflammatory and sedative effects, can promote the disappearance of fever, counteract the increased permeability of capillary walls caused by xylene or histamine, has a significant sedative effect, and can also significantly promote the adrenal cortex function of rats and increase the body's emergency response to pathogen infection; it has a certain inactivation effect on influenza virus type AⅠ, type AⅢ, pneumonia adenovirus (Adv) type Ⅲ, type Ⅳ, and enterosyncytial virus (Rsv) in vitro.

Sorbitol monosaccharide is an isomer of mannitol, and its effect is similar to that of mannitol but weaker. After intravenous injection of concentrated solution (25%) of this product, except for a small part converted into sugar, most of it is excreted in its original form through the kidney. Due to the formation of blood hypertonicity, it can dehydrate the surrounding tissues and brain parenchyma and be excreted from the urine along with the drug, thereby reducing intracranial pressure and eliminating edema. High efficiency appears 2 hours after injection, and the brain edema is gradually calmed down, the tension disappears, the cerebrospinal fluid pressure decreases, it is not metabolized in the body, and is rarely reabsorbed in the renal tubules after glomerular filtration, playing an osmotic diuretic role. 1 Tissue dehydration effect. Increase plasma colloidal osmotic pressure, causing water in tissues (including eyes, brain, cerebrospinal fluid, etc.) to enter the blood vessels, thereby reducing tissue edema, reducing intraocular pressure, intracranial pressure and cerebrospinal fluid volume.

Large doses may cause convulsions