This product is a statin blood lipid regulating drug, belonging to the HMG-CoA reductase inhibitor. It is inactive itself, and the hydrolysis product after oral absorption competitively inhibits the rate-limiting enzyme hydroxymethylglutaryl coenzyme A reductase in the cholesterol synthesis process in the body, reducing the synthesis of cholesterol and increasing the synthesis of low-density lipoprotein receptors. The main site of action is in the liver, resulting in lower blood cholesterol and low-density lipoprotein cholesterol levels, moderately lower serum triglyceride levels and increased blood high-density lipoprotein levels. This has an effect on the prevention and treatment of atherosclerosis and coronary heart disease.

This product is a dihydropyridine calcium channel blocker that inhibits transmembrane calcium influx in vascular smooth muscle and myocardium, but mainly acts on blood vessels, so it has strong vascular selectivity. It causes dilation of systemic blood vessels such as coronary arteries and renal arterioles, producing a hypotensive effect.

1. It can simultaneously relax the coronary arteries in the normal blood supply area and the ischemic area, antagonize spontaneous or ergonovine-induced coronary artery spasm, increase the delivery of myocardial oxygen in patients with coronary artery spasm, and relieve and prevent coronary artery spasm; 2. It can inhibit myocardial contraction, reduce myocardial metabolism, and reduce myocardial oxygen consumption; 3. It can relax peripheral resistance vessels, reduce peripheral resistance, reduce systolic and diastolic blood pressure, and reduce cardiac afterload; 4. It can delay the sinoatrial node function and atrioventricular conduction of the isolated heart; electrophysiological studies on whole animals and humans have not found that this product has the effect of delaying atrioventricular conduction, prolonging the recovery time of the sinoatrial node, and slowing down the sinoatrial node rate.

This product is a synthetic antibacterial drug with bactericidal effect. It is only effective against mycobacteria (mainly bacteria in the growth and reproduction period) and may inhibit the synthesis of mycolic acid in sensitive bacteria and cause cell wall rupture.