CSPC OUYI Pharmaceutical Co., Ltd.

Azithromycin is a 15-membered macrolide antibiotic. In vitro tests have shown that azithromycin has antibacterial effects on a variety of common clinical pathogens, including: Gram-positive aerobic bacteria, Staphylococcus aureus, Streptococcus pyogenes (group A beta; hemolytic streptococci), pneumonia (streptococci), a-hemolytic streptococci (grass-green streptococci) and other streptococci, diphtheria (rod-shaped) bacilli. This product shows cross-resistance to erythromycin-resistant Gram-positive bacteria, including fecal streptococci (enterococci) and various methicillin-resistant Staphylococcus strains.

It is an oxidized derivative of adrenaline and has no adrenaline-mimetic effect, so it does not affect blood pressure and heart rate, but it can enhance the resistance of capillaries to damage, stabilize the acidic mucopolysaccharides in blood vessels and surrounding tissues, reduce the permeability of capillaries, and enhance the retraction effect of damaged capillary ends, making it difficult for blood clots to fall off the tube wall, thereby shortening the hemostasis time, but it does not affect the coagulation process.

It acts on dihydrofolate synthase, interferes with the synthesis of folate reductase, and has a synergistic antibacterial effect with trimethoprim, which is stronger than that of a single drug, and reduces the number of strains that are resistant to it.

It acts on dihydrofolate synthase, interferes with the synthesis of folate reductase, and has a synergistic antibacterial effect with trimethoprim, which is stronger than that of a single drug, and reduces the number of strains that are resistant to it.

Interferes with the function of synthetic folate reductase, and the synergistic antibacterial effect with sulfamethoxazole and sulfadiazine is stronger than that of single drugs, and the number of strains resistant to them is reduced.

This product is a peripheral anticholinergic drug. In addition to its spasmolytic effect on smooth muscle, it also has the effect of blocking ganglia and neuromuscular junctions, but its effect on the central nervous system is weak. It can relieve spasms of smooth muscles in the gastrointestinal tract, bile duct and urinary tract and inhibit gastrointestinal peristalsis.

It inhibits bacterial protein synthesis by hindering bacterial transpeptidation. It is effective against a variety of Gram-positive aerobic bacteria, Gram-negative aerobic bacteria, anaerobic bacteria, sexually transmitted disease microorganisms and other microorganisms. It can reach high concentrations at the site of infection, and its metabolites have no antibacterial activity.