CSPC OUYI Pharmaceutical Co., Ltd.

It has antipyretic and analgesic effects, can inhibit the synthesis and release of hypothalamic prostaglandins, restore the normal responsiveness of the receptor neurons in the body temperature regulation center, and thus have antipyretic and analgesic effects; it also has analgesic, anti-inflammatory and anti-rheumatic effects by inhibiting the synthesis of peripheral prostaglandins, and also has the effect of inhibiting platelet aggregation.

It has antipyretic and analgesic effects, can inhibit the synthesis and release of prostaglandins in the hypothalamus, restore the normal responsiveness of the receptor neurons in the body temperature regulation center, and thus have an antipyretic and analgesic effect.

It is a central nervous system stimulant that can excite the cerebral cortex, increase sensitivity to the outside world, constrict cerebral blood vessels, and enhance the effect of the first two drugs in relieving headaches.

It has antipyretic and analgesic effects, can inhibit the synthesis and release of hypothalamic prostaglandins, restore the normal responsiveness of the receptor neurons in the body temperature regulation center, and thus have antipyretic and analgesic effects; it also has analgesic, anti-inflammatory and anti-rheumatic effects by inhibiting the synthesis of peripheral prostaglandins, and also has the effect of inhibiting platelet aggregation.

It has antipyretic and analgesic effects, can inhibit the synthesis and release of prostaglandins in the hypothalamus, restore the normal responsiveness of the receptor neurons in the body temperature regulation center, and thus have an antipyretic and analgesic effect.

It is a central nervous system stimulant that can excite the cerebral cortex, increase sensitivity to the outside world, constrict cerebral blood vessels, and enhance the effect of the first two drugs in relieving headaches.

1. 5-HT3 receptor antagonism: In the 5-hydroxytryptamine-induced guinea pig isolated colon contraction experiment and rat and ferret heart rate slowing reflex (Bezold-Jarisch reflex) experiment, it showed 5-HT3 receptor antagonism; 2. Anti-malignant tumor drug-induced vomiting inhibition: The vomiting of ferrets induced by cisplatin was inhibited by giving this product before or after the initial vomiting. Cisplatin and other anti-malignant tumor drugs can free 5-hydroxytryptamine from the chromaffin cells in the digestive tract and bind to the 5-HT3 receptors present in the vagus nerve endings in the digestive tract mucosa.

1. It is a non-selective competitive inhibitor of adrenergic β-receptor blocker, blocking β1 and β2 receptors on the heart, reducing the contractile force and contractile speed of the heart, while inhibiting the contraction of vascular smooth muscle, reducing myocardial oxygen consumption, and restoring the balance of oxygen supply and demand of ischemic myocardium at a low level. It can be used to treat angina pectoris; 2. It inhibits the adrenergic excitement of cardiac pacemaker potentials and is used to treat arrhythmias; 3. It can inhibit the release of renin and reduce cardiac output through central and adrenergic neuron blocking, and is used to treat hypertension; 4. It competitively antagonizes the effects of isoproterenol and norepinephrine, blocks β2 receptors, and reduces plasma-related effects.

It promotes the synthesis and release of dopamine in the striatum, reduces the reuptake of dopamine by nerve cells, and has an anti-acetylcholine effect, thereby improving the symptoms of Parkinson's disease patients.