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It can reduce the brain wet weight and brain water content of rats with brain damage caused by local cerebral ischemia of the middle cerebral artery, reduce the scope of cerebral infarction, and significantly prolong the survival time of mice poisoned by sodium nitrite

This product belongs to the tetracycline antibiotics and can still be sensitive to some strains resistant to tetracycline or oxytetracycline. Many Rickettsia, Mycoplasma, Chlamydia, some atypical mycobacteria, and spirochetes are sensitive to this product, but Enterococcus is resistant to it. Others such as Actinomycetes, Bacillus anthracis, Listeria monocytogenes, Clostridium, Nocardia, Vibrio, Brucella, Campylobacter, Yersinia, etc. are sensitive to this product. This product has certain antibacterial activity against Neisseria gonorrhoeae, but penicillin-resistant gonococci are also resistant to methacycline. Due to the widespread use of tetracyclines over the years, common clinical pathogens have serious resistance to methacycline, including Gram-positive bacteria such as Staphylococcus and most Enterobacteriaceae. There is cross-resistance between this product and different varieties of tetracyclines.

It has good antibacterial effect on various Gram-negative and Gram-positive bacteria, and has good effect on various Enterobacteriaceae such as Escherichia coli, Klebsiella, Proteus, Salmonella, Shigella, Enterobacter, Serratia and Pseudomonas aeruginosa. Neisseria and Haemophilus influenzae are moderately sensitive to this product. It also has certain effect on Brucella, Yersinia pestis, Acinetobacter and Campylobacter fetus. It has good antibacterial effect on about 80% of methicillin-sensitive strains of Staphylococcus (including Staphylococcus aureus and coagulase-negative Staphylococci), but methicillin-resistant strains are mostly resistant to this product.

Gentamycin sulfate is an aminoglycoside drug. It has good antibacterial effects on various Gram-negative and Gram-positive bacteria, and has good effects on various Enterobacteriaceae such as Escherichia coli, Klebsiella, Proteus, Salmonella, Shigella, Enterobacter, Serratia and Pseudomonas aeruginosa. Neisseria and Haemophilus influenzae are moderately sensitive to this product. It also has certain effects on Brucella, Yersinia pestis, Acinetobacter and Campylobacter fetus. It has good antibacterial effects on about 80% of methicillin-sensitive strains of Staphylococcus (including Staphylococcus aureus and coagulase-negative Staphylococci), but methicillin-resistant strains are mostly resistant to this product. It has poor effects on Streptococcus and Streptococcus pneumoniae, and Enterococcus are mostly resistant to this product. This product is combined with β-lactams