Histamine H2-receptor antagonists block the effect of histamine on H2-receptors of parietal cells through competitive inhibition mechanism, inhibiting basal gastric acid secretion during the day and at night as well as gastric acid secretion caused by food, histamine, pentagastrin, caffeine and insulin. It does not affect gastric emptying rate and lower esophageal sphincter pressure.

1. Stimulate the pancreatic beta cells to secrete insulin, the prerequisite is that the pancreatic beta cells still have a certain ability to synthesize and secrete insulin; 2. By increasing the level of portal vein insulin or directly acting on the liver, inhibiting liver glycogenolysis and gluconeogenesis, the liver produces and outputs less glucose; 3. It may also increase the sensitivity of extra-pancreatic tissues to insulin and the utilization of sugar (probably mainly through post-receptor effects). Therefore, the overall effect is to lower fasting blood sugar and postprandial blood sugar.

Aminoglycoside antibiotics have good antibacterial effects on various Gram-negative and Gram-positive bacteria. Their mechanism of action is to bind to the 30S subunit of bacterial ribosomes and inhibit the synthesis of bacterial proteins.

Aminoglycoside antibiotics have good antibacterial effects on various Gram-negative and Gram-positive bacteria, and inhibit bacterial protein synthesis by binding to the bacterial ribosome 30S subunit.

Azithromycin is a 15-membered macrolide antibiotic that has antibacterial effects on a variety of Gram-positive aerobic bacteria, Gram-negative aerobic bacteria, anaerobic bacteria, sexually transmitted disease microorganisms and other microorganisms. It mainly binds to the 50S subunit of the bacterial ribosome and inhibits RNA-dependent protein synthesis.