This product is a monoquaternary ammonium steroid medium-acting non-depolarizing muscle relaxant, similar in structure to pancuronium bromide, which blocks the conduction between nerve endings and striated muscles by competing with acetylcholine for nicotinic receptors located at the motor end plate of striated muscles. Unlike depolarizing neuromuscular blocking drugs such as succinylcholine, this product does not cause muscle fiber bundles to tremble. Intravenous injection of 0.08-0.1mg/kg is effective within 1 minute, reaching a peak in 3-5 minutes, and maintaining for 30-90 minutes. The muscle relaxant effect is 3 times stronger than that of tubocurarine chloride; it has no vagus nerve blocking effect. Since vecuronium bromide does not cause an increase in heart rate, it is suitable for patients with myocardial ischemia and heart disease, but the use of vagus nerve excitants and β-receptor blockers is prone to bradycardia. This product has a weak histamine release effect, and there are also bronchospasm and allergic reactions, but they are rare.

Nimodipine is a Ca2 channel blocker that inhibits smooth muscle contraction and relieves vasospasm by preventing Ca2 from entering cells. It has a strong effect on cerebral arteries and can pass through the blood-brain barrier. It is used to prevent vasospasm after subarachnoid hemorrhage, protect and promote memory, promote intellectual recovery, selectively dilate cerebral blood vessels, increase cerebral blood flow, and reduce ischemic brain damage.

Selective serotonin 3 (5-HT3) receptor antagonists, by antagonizing 5-HT3 receptors in peripheral vagal nerve endings and central chemoreceptor areas, block the vomiting reflex caused by factors such as chemotherapy and surgery that promote the release of serotonin from intestinal chromaffin cells and excite the vagal afferent nerves.

This product has a broad-spectrum antimicrobial effect in vitro, including aerobic Gram-negative and Gram-positive bacteria, anaerobes, Rickettsia, spirochetes and Chlamydia. It has bactericidal effects on Haemophilus influenzae, Streptococcus pneumoniae and Neisseria meningitidis; it only has antibacterial effects on anaerobic bacteria such as Staphylococcus aureus, Streptococcus pyogenes, Streptococcus viridans, Group B hemolytic Streptococcus, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Salmonella typhi, Salmonella paratyphi, Shigella, Bacteroides fragilis, etc. Pseudomonas aeruginosa, Acinetobacter, Enterobacter, Serratia marcescens, indole-positive Proteus, methicillin-resistant Staphylococcus and Enterococcus are usually resistant to chloramphenicol. This product is fat-soluble, enters bacterial cells by diffusion, and reversibly binds to the 50S subunit of bacterial ribosomes, inhibiting the formation of peptide chains, thereby preventing protein synthesis.

This product is a vitamin drug. Vitamin K is a necessary substance for the liver to synthesize factors II, VII, IX, and X. Vitamin K deficiency can cause synthesis disorders or abnormalities of these coagulation factors, and clinically bleeding tendency and prolonged prothrombin time can be seen.