Potassium is the main cation in cells, with a concentration of 150-160 mmol/L, while the main cation outside cells is sodium ions, and the serum potassium concentration is only 3.5-5.0 mmol/L. The body mainly relies on Na+-K+ ATPase on the cell membrane to maintain the difference in K+ and Na+ concentrations inside and outside cells. The acid-base balance in the body has an impact on potassium metabolism. For example, when acidosis occurs, H+ enters the cell. In order to maintain the potential difference inside and outside the cell, K+ is released outside the cell, causing or aggravating hyperkalemia. Metabolic disorders can also affect acid-base balance. The normal potassium ion concentration and concentration difference inside and outside cells are closely related to certain functions of cells, such as carbohydrate metabolism, glycogen storage and protein metabolism, excitability and conductivity of nerves and muscles including myocardium, etc.

This product is a phenothiazine antipsychotic, and its mechanism of action is mainly related to its blocking of dopamine receptors (DA2) in the mesolimbic system and mesocortical pathways. It has a blocking effect on dopamine (DA1) receptors, 5-hydroxytryptamine receptors, M-type acetylcholine receptors, and α-adrenaline receptors, and has a wide range of effects. In addition, this product can inhibit the dopamine receptors in the medulla oblongata emetic chemoreceptor area at low doses, and directly inhibit the vomiting center at high doses, producing a strong antiemetic effect. It inhibits the body temperature regulation center and lowers the body temperature. The body temperature can change with changes in the external environment. It blocks the action of peripheral α-adrenaline receptors, dilates blood vessels, causes a drop in blood pressure, and also has a certain effect on the endocrine system.

Phenothiazine antipsychotics block dopamine receptors (DA2) in the mesolimbic system and mesocortical pathways, and have blocking effects on dopamine (DA1) receptors, 5-hydroxytryptamine receptors, M-type acetylcholine receptors, and α-adrenaline receptors; at low doses, they inhibit dopamine receptors in the medulla oblongata emetic chemoreceptor area, and at high doses, they directly inhibit the vomiting center to produce an antiemetic effect; they inhibit the body temperature regulation center to lower body temperature; they block peripheral α-adrenaline receptors to cause vasodilation and a drop in blood pressure; and they have a certain effect on the endocrine system.

As a histamine H1 receptor antagonist, it can counteract the capillary dilation caused by allergic reactions, reduce the permeability of capillaries, and relieve wheezing caused by bronchial smooth muscle contraction. It has a long-lasting antihistamine effect and also has a significant central inhibitory effect, which can increase the effects of anesthetics, analgesics, hypnotics and local anesthetics. This product is mainly metabolized in the liver.