This product is an azole antifungal drug, which has antibacterial effects on Candida, Chromatiaceae, Coccidioides, Histoplasma, Sporothrix, etc., and also has antibacterial activity against Trichophyton, etc. It interferes with the activity of cytochrome P450, inhibits the biosynthesis of ergosterol in fungal cell membranes, damages cell membranes and changes their permeability, leading to leakage of intracellular substances; inhibits the biosynthesis of fungal triglycerides and phospholipids, inhibits the activity of oxidases and peroxidases, causes the accumulation of intracellular hydrogen peroxide, and leads to cell submicrostructure degeneration and cell necrosis. It can inhibit the process of Candida albicans from transforming from spores to invasive hyphae.

This product belongs to the aminoglycoside antibiotics, and its antibacterial spectrum is similar to that of gentamicin. It has antibacterial effects on a variety of Gram-negative bacteria, and its antibacterial effect on Pseudomonas aeruginosa is 3 to 5 times stronger than that of gentamicin. Its mechanism of action is to bind to the 30S subunit of the bacterial ribosome and inhibit the synthesis of bacterial proteins.

Quinine is a quinoline derivative that can bind to the DNA of malarial parasites to form a complex that inhibits DNA replication and RNA transcription, thereby inhibiting the protein synthesis of the parasites. In addition, quinine can reduce the oxygen consumption of malarial parasites, inhibit the phosphorylase in malarial parasites and interfere with their sugar metabolism. Quinine also causes hemochromatin aggregation. In the blood, a certain concentration of quinine can cause premature rupture of parasitized red blood cells, thereby preventing the maturation of schizonts. This product is ineffective in the early stage of malaria, and a long course of treatment can cure malignant malaria, but it has no direct effect on the gametocytes of malignant malaria, so it cannot interrupt transmission.

Small doses act on the higher centers of the cerebral cortex, promoting mental excitement, while larger doses can excite the respiratory center and vasomotor center of the medulla oblongata.

This product is a broad-spectrum aminoglycoside antibiotic, and its mechanism of action is mainly to inhibit bacterial protein synthesis. It has antibacterial effects on common Gram-negative bacteria in the eye.