Broad-spectrum semi-synthetic penicillin has a broad-spectrum killing effect on Gram-positive and Gram-negative bacteria. It has a strong antibacterial effect on hemolytic streptococci, pneumococci and non-penicillinase-producing staphylococci, which is similar to or slightly inferior to penicillin. It also has a good antibacterial effect on viridans streptococci, and is better than penicillin on enterococci and Listeria. It has antibacterial effects on Corynebacterium diphtheriae, Bacillus anthracis, Actinomyces, Haemophilus influenzae, Bordetella pertussis, and Neisseria.

Acid-resistant and enzyme-resistant semi-synthetic penicillin is effective against penicillin-resistant Staphylococcus aureus. It can make up for the shortcomings of ampicillin used alone and enhance the overall antibacterial effect.

By inhibiting bacterial DNA gyrase and topoisomerase IV, it inhibits the replication, transcription, and repair process of bacterial DNA. It has antibacterial activity against the following microorganisms: 1. Gram-positive bacteria: Staphylococcus aureus (limited to strains sensitive to methicillin), coagulase-negative Staphylococci, Streptococcus pneumoniae and other Streptococcus strains. 2. Gram-negative bacteria: Haemophilus (influenza and parainfluenza), Moraxella catarrhalis, Neisseria, Acinetobacter, Klebsiella pneumoniae, Enterobacter cloacae, Proteus (Proteus mirabilis and Proteus vulgaris), Pseudomonas aeruginosa, Citrobacter and Escherichia coli. 3. Other microorganisms: Chlamydia pneumoniae, Legionella pneumophila, Mycoplasma pneumoniae.

By inhibiting bacterial DNA gyrase and topoisomerase IV, it inhibits bacterial DNA replication, transcription, and repair processes. It has antibacterial activity against the following microorganisms: Gram-positive bacteria (such as Staphylococcus aureus, Streptococcus pneumoniae, etc.), Gram-negative bacteria (such as Haemophilus, Moraxella catarrhalis, Neisseria, Acinetobacter, Klebsiella pneumoniae, Enterobacter cloacae, Proteus, Pseudomonas aeruginosa, Citrobacter and Escherichia coli) and other microorganisms (such as Chlamydia pneumoniae, Legionella pneumophila, Mycoplasma pneumoniae).

By inhibiting bacterial DNA gyrase and topoisomerase IV, it inhibits bacterial DNA replication, transcription, and repair processes. It has antibacterial activity against the following microorganisms: Gram-positive bacteria (such as Staphylococcus aureus, Streptococcus pneumoniae, etc.), Gram-negative bacteria (such as Haemophilus, Moraxella catarrhalis, Neisseria, Acinetobacter, Klebsiella pneumoniae, Enterobacter cloacae, Proteus, Pseudomonas aeruginosa, Citrobacter and Escherichia coli) and other microorganisms (such as Chlamydia pneumoniae, Legionella pneumophila, Mycoplasma pneumoniae).

Ampicillin sodium is a broad-spectrum semi-synthetic penicillin. This product has a strong antibacterial effect on hemolytic streptococci, Streptococcus pneumoniae and non-penicillinase-producing Staphylococci, which is similar to or slightly inferior to penicillin. Ampicillin also has a good antibacterial effect on viridans streptococci, and is better than penicillin on enterococci and Listeria. This product has antibacterial activity against Corynebacterium diphtheriae, Bacillus anthracis, Actinomyces, Haemophilus influenzae, Bordetella pertussis, Neisseria and anaerobic bacteria except Bacteroides fragilis. Some Proteus mirabilis, Escherichia coli, Salmonella and Shigella are sensitive to this product. Ampicillin exerts its bactericidal effect by inhibiting bacterial cell wall synthesis.