Hainan Lingkang Pharmaceutical Co., Ltd.

It inhibits the synthesis of bacterial cell wall, has good permeability to the cell wall, is stable to β-lactamase, has a strong affinity for penicillin-binding proteins 1A, 1B and 3, and can strongly inhibit the cross-linking of cell wall mucopeptides.

This product has a broad-spectrum antibacterial effect, especially high antibacterial activity against aerobic Gram-negative bacilli. It has good antibacterial activity in vitro against the following bacteria: most bacteria of the Enterobacteriaceae family, including Citrobacter, Enterobacter cloacae, Enterobacter aerogenes, Escherichia coli, Klebsiella, Proteus, Salmonella, Shigella, Vibrio, Yersinia, etc. It often has antibacterial activity against multi-drug resistant bacteria. It has high antibacterial activity against penicillin-resistant Neisseria gonorrhoeae, enzyme-producing Haemophilus influenzae and Moraxella. It has antibacterial activity against most strains of Pseudomonas such as Pseudomonas aeruginosa. This product has antibacterial activity against methicillin-sensitive Staphylococcus aureus, and only moderate antibacterial activity against Streptococcus pneumoniae, hemolytic Streptococcus and Enterococcus faecalis. It has good antimicrobial activity against Chlamydia trachomatis, Mycoplasma, Legionella, and also has antibacterial activity against Mycobacterium tuberculosis and atypical mycobacteria. The antibacterial activity against anaerobic bacteria is poor. Enoxacin is a bactericide that acts on the A subunit of bacterial DNA helicase, inhibiting DNA synthesis and replication, leading to bacterial death.

This product has a broad-spectrum antibacterial effect, especially high antibacterial activity against aerobic Gram-negative bacilli. It has good antibacterial activity in vitro against the following bacteria: most bacteria of the Enterobacteriaceae family, including Citrobacter, Enterobacter cloacae, Enterobacter aerogenes, Escherichia coli, Klebsiella, Proteus, Salmonella, Shigella, Vibrio, Yersinia, etc. It often has antibacterial activity against multi-drug resistant bacteria. It has high antibacterial activity against penicillin-resistant Neisseria gonorrhoeae, enzyme-producing Haemophilus influenzae and Moraxella. It has antibacterial activity against most strains of Pseudomonas such as Pseudomonas aeruginosa. This product has antibacterial activity against methicillin-sensitive Staphylococcus aureus, and only moderate antibacterial activity against Streptococcus pneumoniae, hemolytic Streptococcus and Enterococcus faecalis. It has good antimicrobial activity against Chlamydia trachomatis, Mycoplasma, Legionella, and also has antibacterial activity against Mycobacterium tuberculosis and atypical mycobacteria. The antibacterial activity against anaerobic bacteria is poor. Enoxacin is a bactericide that acts on the A subunit of bacterial DNA helicase, inhibiting DNA synthesis and replication, leading to bacterial death.

Second-generation cephalosporin antibiotics, which are rapidly hydrolyzed into cefuroxime after entering the body, have strong antibacterial effects on most Gram-positive cocci, have good effects on diphtheria Corynebacterium and Gram-positive anaerobic bacteria, have strong activity against Escherichia coli, Proteus mirabilis, Klebsiella pneumoniae and Haemophilus influenzae, are sensitive to some Enterobacter aerogenes, indole-positive Proteus and Providencia, are also sensitive to Salmonella typhi, Shigella, Neisseria gonorrhoeae and Neisseria meningitidis, have poor antibacterial effects on Bacteroides fragilis, and are resistant to Serratia, Alcaligenes, Acinetobacter and Pseudomonas aeruginosa. The mechanism of action is to bind to penicillin-binding proteins (PBPs) on the bacterial cell membrane, inhibit the synthesis of bacterial septa and cell walls, make the bacteria longer in shape, and finally dissolve and die.

Bactericidal effect achieved by inhibiting the biosynthesis of sensitive bacterial cell walls

It has an irreversible inhibitory effect on most important β-lactamases produced by β-lactam antibiotic-resistant strains, and can protect β-lactam antibiotics from hydrolysis and destruction by β-lactamases of resistant bacteria; it can combine with certain penicillin-binding proteins to enhance its effect on sensitive strains.

It is a third-generation cephalosporin that kills bacteria by inhibiting the biosynthesis of the cell wall of sensitive bacteria.

It has an irreversible inhibitory effect on most important β-lactamases produced by β-lactam antibiotic-resistant strains, and can protect β-lactam antibiotics from hydrolysis and destruction by β-lactamases of resistant bacteria; it can bind to certain penicillin-binding proteins to enhance the sensitivity to compound preparations