Reyoung Pharmaceutical Co., Ltd.

A broad-spectrum semi-synthetic penicillin with antibacterial effects on Gram-positive and Gram-negative bacteria. It has a strong antibacterial effect on hemolytic streptococci, Streptococcus pneumoniae and non-penicillinase-producing Staphylococci. It also has a good antibacterial effect on viridans streptococci. Its effect on Enterococci and Listeria is better than penicillin. It is effective against Corynebacterium diphtheriae, Bacillus anthracis, Actinomyces, Haemophilus influenzae, Bordetella pertussis, Neisseria, etc.

Acid-resistant and enzyme-resistant semi-synthetic penicillin, effective against penicillin-resistant Staphylococcus aureus. When used in combination with ampicillin, they can enhance each other's effects and make up for the shortcomings of each used alone.

Amoxicillin is a broad-spectrum penicillin antibiotic, and potassium clavulanate can protect it from hydrolysis by β-lactamase. It has good effects on enzyme-producing Staphylococcus aureus, Staphylococcus epidermidis, coagulase-negative Staphylococci and enterococci, and also has good antibacterial activity against certain β-lactamase-producing Enterobacteriaceae, Haemophilus influenzae, Moraxella catarrhalis, Bacteroides fragilis, etc.

Potassium clavulanate itself has only weak antibacterial activity, but it has a strong broad-spectrum β-lactamase inhibitory effect and can protect amoxicillin from β-lactamase hydrolysis.

Ticarcillin is a broad-spectrum penicillin-type bactericide that destroys bacterial cell walls. When combined with clavulanic acid, it can restore the sensitivity of β-lactamase-producing bacteria.

Clavulanic acid is an irreversible and highly effective β-lactamase inhibitor. It has little antibacterial effect alone, but it can effectively block the activity of β-lactamase and enhance the antibacterial effect of ticarcillin.

This product has a broad-spectrum antibacterial effect, especially high antibacterial activity against aerobic Gram-negative bacilli. It has good antibacterial activity in vitro against the following bacteria: most bacteria of the Enterobacteriaceae family, including Citrobacter, Enterobacter cloacae, Enterobacter aerogenes, Escherichia coli, Klebsiella, Proteus, Salmonella, Shigella, Vibrio, Yersinia, etc. It often has antibacterial activity against multi-drug resistant bacteria. It has high antibacterial activity against penicillin-resistant Neisseria gonorrhoeae, enzyme-producing Haemophilus influenzae and Moraxella. It has antibacterial activity against most strains of Pseudomonas such as Pseudomonas aeruginosa. This product has antibacterial activity against methicillin-sensitive Staphylococcus aureus, and only moderate antibacterial activity against Streptococcus pneumoniae, hemolytic Streptococcus and Enterococcus faecalis. It has good antimicrobial activity against Chlamydia trachomatis, Mycoplasma, Legionella, and also has antibacterial activity against Mycobacterium tuberculosis and atypical mycobacteria. The antibacterial activity against anaerobic bacteria is poor. Enoxacin is a bactericide that acts on the A subunit of bacterial DNA helicase, inhibiting DNA synthesis and replication, leading to bacterial death.