On ECHEMI
Home > Drugs > Methylcobalamin Injection

Methylcobalamin Injection

Function and Efficacy

Pharmacology (1) Methylcobalamin is an endogenous coenzyme B12. It plays an important role as a coenzyme of methionine synthase in the transmethylation reaction of homocysteine to methionine. (2) Methylcobalamin is easily transferred to the organelles of nerve cells, thereby promoting the synthesis of nucleic acids and proteins. Methylcobalamin is more easily transferred into the organelles of rat nerve cells than cyanocobalamin. In experiments on mouse brain cells and spinal cord nerve cells, it participates in the process of synthesizing thymidine from deoxyuridine, promoting the utilization of folic acid and the metabolism of nucleic acids. Moreover, methylcobalamin can promote the synthesis of nucleic acids and proteins in rats more than cobalamin. (3) Promoting intra-axonal transport and axonal regeneration has an important effect on the sitting of diabetic rats caused by streptozotocin.

Ingredients

The main ingredient of this product is methylcobalamin, and its chemical name is: Coα-[α-(5,6-dimethylbenzimidazolyl)]-Coβ-methylcobaltamide.

Name Description Content CAS NO. Manufacturer
MecobalaminIngredients

Methylcobalamin is an endogenous coenzyme B12. It plays an important role as a coenzyme of methionine synthase in the transmethylation reaction of homocysteine to methionine. It is easily transferred to the organelles of nerve cells, thereby promoting the synthesis of nucleic acids and proteins. It promotes axonal transport and axonal regeneration, and has a certain improvement effect on sciatica neuropathy caused by streptozotocin in diabetic rats.

More
13422-55-4 29

Appearance

This product is a red clear liquid.

Indication

1. Used for peripheral neuropathy. 2. Treatment of megaloblastic anemia caused by vitamin B12 deficiency.

Usage and Dosage

1. For adults with peripheral neuropathy, take 0.5 mg once a day, 3 times a week, intramuscularly or intravenously. The dosage can be increased or decreased according to age and symptoms. 2. For adults with megaloblastic anemia, take 0.5 mg once a day, 3 times a week, intramuscularly or intravenously. After about two months of administration, 0.7 mg can be given every 1 to 3 months as a maintenance treatment.

Adverse Reactions

1 Serious adverse reactions (frequency unknown) Allergic reactions: May cause allergic reactions such as decreased blood pressure and difficulty breathing. Patients should be closely observed. If such reactions occur, the medication should be discontinued immediately and appropriate measures should be taken. 2 Other adverse reactions (1) Allergic reactions: Rash occurs ((2) Others: Headache, fever (<0.1%): Sweating, pain at the intramuscular injection site, nodules (frequency unknown). If these adverse reactions occur, the medication should be discontinued.

Precautions

It is contraindicated for those who are allergic to this product or its ingredients.

Special Population Medication

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: The safety of using this drug in pregnant and lactating women is not yet clear. Precautions for the elderly: Not yet clear.

Drug Interactions

Not yet clear.

Storage

Keep in a dark and airtight place. +24 months.

Packaging Specification

1ml:0.5mg

Validity Period

24 months.

Manufacturer

STAR Pharmaceutical Pte.ltd

  • Founded in:

    1993-08-28
  • Address:

    3rd Floor, Office Building, No. 6 Shunda Road, Jiangdong New District, Haikou City, Hainan Province
  • Tax NO.:

    91469002620007633W
  • Registered Funds:

    HK$50 million
  • Website:

  • Email:

Feedback & Suggestions
Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.