Thyroid tablets
Function and Efficacy
1. This product is a thyroid hormone drug. 2. The main ingredients of this product are thyroid hormones, including thyroxine (T4) and triiodothyronine (T3). It has the effect of promoting catabolism (heat-raising effect) and anabolism, and has an important impact on the normal metabolism and growth and development of the human body, and is very important for the development of the central nervous system of infants and young children. 3. The basic function of thyroid hormone is to induce the synthesis of new proteins including special enzyme systems, regulate the metabolism of three major substances: protein, carbohydrates and fats, as well as water, salt and vitamins. Because thyroid hormone induces the synthesis of cell membrane Na-K pumps and enhances their activity, energy metabolism is enhanced. Thyroid hormones (mainly T3) bind to specific receptors in the nucleus, which undergo conformational changes to form dimers. The activated receptors bind to specific sequences on DNA, thyroid hormone response elements, thereby regulating the transcription and expression of genes (target genes of thyroid hormones) and promoting the synthesis of new proteins (mainly enzymes).
Ingredients
L-Thyroxine
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| L-ThyroxineIngredients |
This product is a thyroid hormone drug. The main ingredients of thyroid hormones include thyroxine (T4) and triiodothyronine (T3). It has the effect of promoting catabolism (heat-raising effect) and anabolism, and has an important impact on the normal metabolism and growth and development of the human body. It is very important for the development of the central nervous system of infants and young children. The basic function of thyroid hormone is to induce the synthesis of new proteins including special enzyme systems, regulate the metabolism of three major substances: protein, carbohydrates and fat, as well as water, salt and vitamins. Because thyroid hormone induces the synthesis of cell membrane Na-K pumps and enhances their activity, energy metabolism is enhanced. Thyroid hormone (mainly T3) binds to specific receptors in the nucleus, which undergo conformational changes to form dimers. The activated receptors bind to specific sequences on DNA and thyroid hormone response elements, thereby regulating the transcription and expression of genes (target genes of thyroid hormones) and promoting the synthesis of new proteins (mainly enzymes). More |
51-48-9 | 0 |
Indication
Used for hypothyroidism caused by various reasons.
Usage and Dosage
1. Common dosage for adults: oral administration, starting with 10-20 mg per day, gradually increasing, maintenance dose is generally 40-120 mg per day, a few patients need 160 mg per day. 2. Complete replacement dose for infants and children: 8-15 mg for children under 1 year old; 20-45 mg for 1-2 years old; 45-60 mg for 2-7 years old; 60-120 mg for those over 7 years old. The starting dose should be 1/3 of the complete replacement dose, and the dose should be increased gradually. Since the content of T3 and T4 in this product and the ratio of the two are not constant, the dose should be adjusted according to clinical symptoms and T3, T4, and TSH examinations during treatment.
Adverse Reactions
Thyroid tablets have no adverse reactions if used in appropriate dosage. Overdose may cause tachycardia, palpitations, angina, arrhythmia, headache, nervousness, excitement, restlessness, insomnia, skeletal muscle spasms, muscle weakness, tremor, sweating, flushing, heat intolerance, diarrhea, vomiting, weight loss and other symptoms similar to hyperthyroidism. All symptoms can be eliminated by reducing the dosage or stopping the drug.
Precautions
1. Elderly people should use with caution. 2. Pregnant women should use with caution. 3. Patients with angina pectoris, coronary heart disease and tachyarrhythmia should not use this product.
Special Population Medication
Precautions for children: This test has not been conducted and there is no reliable reference literature. Precautions for pregnancy and lactation: Use with caution in pregnant women. Precautions for the elderly: Use with caution in the elderly.
Drug Interactions
1. Diabetic patients taking thyroid hormones should appropriately increase the dose of insulin or hypoglycemic drugs depending on blood sugar levels. 2. When thyroid hormones are used in combination with anticoagulants such as dicoumarol, the latter's anticoagulant effect is enhanced, which may cause bleeding; the dose of anticoagulants should be adjusted according to the prothrombin time. 3. When this type of drug is used in combination with tricyclic antidepressants, the effects and toxic side effects of both types of drugs are enhanced, so attention should be paid to adjusting the dose. 4. For those taking estrogen or contraceptives, the dose of thyroid hormone should be appropriately adjusted when used in combination because the level of thyroxine-binding globulin in the blood increases. 5. Cholestyramine or cholestipol can weaken the effect of thyroid hormones. When the two types of drugs are used together, they should be taken 4-5 hours apart, and thyroid function should be measured regularly. 6. Beta-adrenergic receptor blockers can reduce the conversion of T4 to T3 in peripheral tissues, so care should be taken when used in combination.
Storage
Keep away from light and store in sealed container.
Packaging Specification
40mg
Validity Period
24 months
Manufacturer
Tianjin Jun'an Biopharmaceutical Co., Ltd.
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Founded in:
2001-08-28 -
Address:
Jiuyuan Industrial Park, Baodi Development Zone, Tianjin -
Tax NO.:
911202247303703966 -
Registered Funds:
3.841299 yuan -
Email: