Sodium Oxybate Injection

After intravenous injection, drowsiness occurs 3 to 5 minutes after this product is injected intravenously, and deep sleep occurs after 10 to 15 minutes. The effect lasts for 90 to 120 minutes, and sometimes can last for several hours. 1 Central nervous system: This product inhibits central nervous system activity, mainly due to the excitation of GABA receptors. The general dose acts on the cerebral cortex, and the large dose also affects the brainstem and midbrain, producing a hypnotic effect, but does not inhibit the reticular activation system, and is prone to muscle twitching, involuntary movements and extrapyramidal symptoms. This product has no analgesic effect. 2 Circulatory system: It has an excitatory effect on the circulatory system, causing slightly higher blood pressure, slow and strong pulse, no effect on cardiac output, and no increase in intracranial pressure. It promotes K to enter cells, and the electrocardiogram can show a flat or inverted T wave, or the appearance of a U wave. 3 Respiratory system: The general dose can slightly slow down the respiratory rate and slightly increase the tidal volume. However, rapid injection of a large dose can produce respiratory depression. 4 It can make the throat reflex sluggish, inhibited, and the mandible relaxed. After surface anesthesia, endotracheal intubation can be performed.

The main ingredients of this product are: sodium oxybate. Molecular formula: C4H7NaO2 Molecular weight: 126.09

Intravenous general anesthetic. Often used in combination with general anesthetics or anesthetic adjuvants. Used for the induction and maintenance of combined general anesthesia.

Common dosage: 60-80 mg/kg body weight for general anesthesia induction intravenous injection, injection speed is about 1g per minute. The maximum dosage for children is 100 mg/kg body weight. The induction dosage for adults is 2-5g, and 1-2g is added every 1-2 hours for patients with long surgery time. The maintenance dosage for general anesthesia is 12-80 mg/kg body weight for intravenous injection. The dosage for basic anesthesia for adults is 50-60 mg/kg body weight, and for children it is 60-80 mg/kg body weight. Maximum dosage: The total dosage for adults is 300 mg/kg body weight at one time.

1. Extrapyramidal symptoms may occur during anesthesia induction and awakening. 2. Respiratory secretions increase after medication. 3. This product can inhibit breathing and cause a slowing of the respiratory rate.

Severe hypokalemia.

1. When used with atropine, it can reduce the excitatory effect of this product on the parasympathetic nerves and prevent the occurrence of slow heart rate. 2. When used with muscle relaxants, it can enhance the muscle relaxant effect. 3. When used with barbiturates and tranquilizers, it can reduce extrapyramidal symptoms.

Keep tightly closed in a cool, dark and dry place.

10ml:2.5g

Xi`an Han Feng Pharmaceutical Co., Ltd.

• Founded in:

  2003-03-11

• Address:

  No. 15, Wenji Road, Lantian County Industrial Park

• Tax NO.:

  91610122742829723D

• Registered Funds:

  25 million yuan

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