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naproxen suppository

Function and Efficacy

This product is a non-steroidal anti-inflammatory drug. Its analgesic, anti-inflammatory and antipyretic effects work by inhibiting the synthesis of prostaglandins.

Ingredients

Naproxen. Its chemical name is: ()-α-methyl-6-methoxy-2-naphthylacetic acid.

Name Description Content CAS NO. Manufacturer
NaproxenIngredients

This product is a non-steroidal anti-inflammatory drug. Its analgesic, anti-inflammatory and antipyretic effects work by inhibiting the synthesis of prostaglandins.

More
22204-53-1 30

Appearance

The product is a milky white or slightly yellow conical suppository

Indication

It is used to treat rheumatic and rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, gout, arthritis, and tenosynovitis. It can also be used to relieve pain caused by musculoskeletal sprains, contusions, injuries, and dysmenorrhea.

Usage and Dosage

Rectal administration: 0.125-0.25 g once, 0.5 g per day, follow doctor's advice if necessary

Adverse Reactions

(1) Skin itching, shortness of breath, dyspnea, asthma, tinnitus, lower limb edema, stomach burning sensation, indigestion, stomach pain or discomfort, constipation, dizziness, drowsiness, headache, nausea and vomiting, etc. (2) Blurred vision or visual impairment, hearing loss, diarrhea, palpitations and sweating, etc. (3) Gastrointestinal bleeding, kidney damage (allergic nephritis, kidney disease, renal papillary necrosis and renal failure, etc.), urticaria, allergic rash, depression, muscle weakness, bleeding or granulocytopenia and liver damage, etc. are less common.

Precautions

This product should not be used by people with a history of allergy to this product or similar drugs, or those who have experienced asthma, rhinitis, and nasal polyposis syndrome caused by aspirin or other non-steroidal anti-inflammatory drugs. It is also contraindicated in patients with active gastric and duodenal ulcers.

Special Population Medication

Precautions for children: This experiment has not been conducted and there are no reliable references. Precautions for pregnancy and lactation: The effects of this product on the fetus have not been established. Since other non-steroidal anti-inflammatory drugs can cause premature closure of the fetal ductus arteriosus and can inhibit prostaglandins, leading to dystocia or prolonged labor, pregnant women should not use it. Since this product can be secreted into breast milk, it is contraindicated for lactating women. Precautions for the elderly: This experiment has not been conducted and there are no reliable references.

Drug Interactions

(1) When used with alcohol or other anti-inflammatory drugs, gastrointestinal adverse reactions increase and there is a risk of ulcers. (2) When used with anticoagulants such as heparin and dicoumarol, bleeding time is prolonged. Bleeding tendency may occur and there is a possibility of gastrointestinal ulcers. (3) This product can reduce the sodium excretion and antihypertensive effects of furosemide. (4) This product can inhibit the excretion of lithium in the urine and increase the blood concentration of lithium. (5) When used with probenecid, the blood concentration of this product increases and T1/2 is prolonged. The efficacy can be increased, but the toxicity reaction is also increased accordingly.

Storage

Keep in dark place and sealed below 30℃

Packaging Specification

0.4g

Validity Period

24 months

Manufacturer

Huludao Guodi Pharmaceutical Co., Ltd.

  • Founded in:

    2000-06-29
  • Address:

    Huludao Gaoqiao Economic Development Zone
  • Tax NO.:

    91211404123720542A
  • Registered Funds:

    16.18 million yuan
  • Website:

  • Email:

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