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Cefaclor Capsules

Function and Efficacy

Antibacterial drug. The beta-lactamase produced by Staphylococcus aureus is relatively stable, so it has a strong antibacterial effect on Gram-positive bacteria; the beta-lactamase produced by Gram-negative bacteria is unstable, so it has a weaker effect on Gram-negative bacteria and is ineffective against Pseudomonas aeruginosa and anaerobic bacteria.

Ingredients

Cefaclor Chemical name (6R,7R)-7-[(R)-2-amino-2-phenylacetylamino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid monohydrate Molecular formula C15H14ClN3O4SH2O Molecular weight 385.82

Name Description Content CAS NO. Manufacturer
CefaclorIngredients

Antibacterial drug. The beta-lactamase produced by Staphylococcus aureus is relatively stable, so it has a strong antibacterial effect on Gram-positive bacteria; the beta-lactamase produced by Gram-negative bacteria is unstable, so it has a weaker effect on Gram-negative bacteria and is ineffective against Pseudomonas aeruginosa and anaerobic bacteria.

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53994-73-3 29

Appearance

Capsules, the contents are white to light yellow powder.

Indication

This product is mainly used for respiratory system, urinary system, ENT, skin and soft tissue infections caused by sensitive bacteria.

Usage and Dosage

Oral: The usual adult dose is 0.25g once, 3 times a day. The dose can be doubled for patients with severe infection, but the total daily amount should not exceed 4.0g. Or follow the doctor's advice.

Adverse Reactions

1 Gastrointestinal: diarrhea, stomach discomfort, nausea, vomiting, etc. 2 Allergic reactions: urticaria, rash, eosinophilia, vulvar itching. 3 Others: mild increase in aminotransferase, plasma urea nitrogen (BUN) and creatinine (Cr), proteinuria, casts, etc.

Precautions

Contraindicated in patients allergic to cephalosporins

Special Population Medication

Precautions for children: This experiment has not been conducted and there is no reliable reference. Precautions for pregnancy and lactation: Use with caution in pregnant and lactating women. Precautions for the elderly: This experiment has not been conducted and there is no reliable reference.

Drug Interactions

The combined use of strong diuretics such as furosemide, ethacrynic acid, bumetanide, antineoplastic drugs such as carmustine, streptozocin, and nephrotoxic drugs such as aminoglycoside antibiotics with this product may increase nephrotoxicity. Clavulanic acid can enhance the antibacterial activity of this product against certain Gram-negative bacteria that are resistant to this product due to the production of b-lactamase. Oral administration of probenecid can delay the excretion of this product.

Storage

Keep away from light, seal tightly, and store in a cool, dark and dry place.

Packaging Specification

0.25 g (calculated as C15H14CIN3O4S)

Validity Period

24 months

Manufacturer

Shandong Lukang Pharmaceutical Co., Ltd.

  • Founded in:

    1993-02-15
  • Address:

    No. 88, Deyuan Road, Jining High-tech Zone, Shandong Province
  • Tax NO.:

    913700001659297311
  • Registered Funds:

    880.229735 yuan
  • Website:

  • Email:

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