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Felodipine Tablets

Function and Efficacy

When taking this product, taking drugs that affect cytochrome P450 at the same time can affect the blood concentration of felodipine. Enzyme inducers (such as phenytoin, carbamazepine, barbiturates) can cause a decrease in the blood concentration of felodipine. Enzyme inhibitors (cimetidine) can cause an increase in the blood concentration of felodipine. Although felodipine has a high degree of plasma protein binding, it does not affect the binding degree of other plasma protein-bound drugs (such as warfarin).

Ingredients

The main ingredient of this product is felodipine. Its chemical name is 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3-pyridinedicarboxylic acid ethyl ester methyl ester.

Name Description Content CAS NO. Manufacturer
FelodipineIngredients

When taking this product, taking drugs that affect cytochrome P450 at the same time can affect the blood concentration of felodipine. Enzyme inducers (such as phenytoin, carbamazepine, barbiturates) can cause a decrease in the blood concentration of felodipine. Enzyme inhibitors (cimetidine) can cause an increase in the blood concentration of felodipine. Although felodipine has a high degree of plasma protein binding, it does not affect the binding degree of other plasma protein-bound drugs (such as warfarin).

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Appearance

This product is white tablets.

Indication

Used for the treatment of mild to moderate essential hypertension.

Usage and Dosage

Oral: Starting dose 2.5 mg, twice a day, or as directed by a doctor. The usual maintenance dose is 5 mg or 10 mg per day. If necessary, the dose can be further increased, or other antihypertensive drugs can be added.

Adverse Reactions

This product is the same as other calcium antagonists. Some patients may experience flushing, headache, dizziness, palpitations and fatigue. Most of these reactions are dose-dependent and appear temporarily within a short period of time after the dose is increased, and disappear as the application time increases. This product is the same as other dihydropyridine drugs. It can cause dose-related ankle swelling, gums or periodontitis. Patients may experience mild gum swelling after taking the drug, and may also experience rash and itching.

Precautions

Pregnant women and those who are allergic to this product are prohibited from using it.

Special Population Medication

Precautions for children: This test has not been conducted and there is no reliable reference. Precautions for pregnancy and lactation: Pregnant women and those who are allergic to this product are prohibited. Precautions for the elderly: This test has not been conducted and there is no reliable reference.

Drug Interactions

1 When taking this product, taking drugs that affect cytochrome P450 at the same time may affect the blood concentration of felodipine. 2 Enzyme inducing drugs (such as phenytoin, carbamazepine, barbiturates) can cause a decrease in the blood concentration of felodipine. 3 Enzyme inhibitors (cimetidine) can cause an increase in the blood concentration of felodipine. Although felodipine has a high degree of plasma protein binding, it does not affect the binding degree of other plasma protein binding drugs (such as warfarin).

Storage

Keep away from light and store in sealed container.

Packaging Specification

10mg

Validity Period

36 months

Manufacturer

Zhejiang Sukean Pharmaceutical Co., Ltd.

  • Founded in:

    2010-12-21
  • Address:

    No. 829, Changfuhang Road, Qianjin Street, Qiantang District, Hangzhou City, Zhejiang Province
  • Tax NO.:

    91330100566970364L
  • Registered Funds:

    165 million yuan
  • Website:

  • Email:

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