Omeprazole enteric-coated capsules

Proton pump inhibitor. This product is a fat-soluble weakly alkaline drug that is easily concentrated in an acidic environment. Therefore, after oral administration, it can be specifically distributed in the secretory tubules of the gastric mucosal parietal cells and converted into the active form of sulfenamide in this high-acid environment. It then irreversibly combines with the sulfhydryl group of the H,K-ATPase (also known as the proton pump) in the secretory membrane of the parietal cells through a disulfide bond to form a complex of sulfenamide and the proton pump, thereby inhibiting the activity of the enzyme and blocking the final step of gastric acid secretion. Therefore, this product has a strong and lasting inhibitory effect on gastric acid secretion caused by various reasons.

The main ingredient of this product is omeprazole. Its chemical name is 5-methoxy-2-{[(4-methoxy-3,5-dimethyl-2-pyridyl)-methyl]-sulfoxide}-1H-benzimidazole. Molecular formula: C17H19N3O3S Molecular weight: 345.41

The content of this product is white or off-white enteric-coated granules.

It is suitable for gastric ulcer, duodenal ulcer, stress ulcer, reflux esophagitis and Zollinger-Ellison syndrome (gastrinoma).

Oral administration, do not chew. 1 Peptic ulcer: 20 mg once, 1-2 times a day. Swallow in the morning or once in the morning and evening. The treatment course for gastric ulcer is usually 4-8 weeks, and the treatment course for duodenal ulcer is usually 2-4 weeks. 2 Reflux esophagitis: 20-60 mg once, 1-2 times a day. Swallow in the morning or once in the morning and evening. The treatment course is usually 4-8 weeks. 3 Zollinger-Ellison syndrome: 60 mg once, once a day. The total daily dose can be adjusted to 20-120 mg according to the condition. If the total daily dose exceeds 80 mg, it should be taken in two doses.

Common adverse reactions of this product are: headache, diarrhea, nausea, vomiting, constipation, abdominal pain and bloating. Occasionally, dizziness, drowsiness, fatigue, sleep disorders, paresthesia, rash, itching, urticaria, abnormal liver function tests, etc. are seen. Rarely, hyperhidrosis, peripheral angioedema, hyponatremia; angioedema, fever and anaphylactic shock; leukopenia, thrombocytopenia, agranulocytosis, pancytopenia; reversible mental confusion, irritability, depression, aggression and hallucinations; gynecomastia; dry mouth, abnormal taste, stomatitis, candidiasis; hair loss, photosensitivity, erythema multiforme; hepatic encephalopathy (previous severe liver disease), icteric or non-icteric hepatitis, liver failure; bronchospasm; arthralgia, myalgia, muscle fatigue; interstitial nephritis; blurred vision.

It is contraindicated for patients who are allergic to this product, those with severe renal insufficiency and infants.

Precautions for children: It is forbidden for infants and young children. Precautions for pregnancy and lactation: Although this product has no teratogenic effect in animal experiments, it should generally not be used by pregnant women, and should also be used with caution for lactating women. Precautions for the elderly: It is not clear yet.

1 Avoid using it at the same time with oral imidazole antifungal drugs such as ketoconazole, itraconazole, miconazole and fluconazole. 2 The combined use of omeprazole and clarithromycin can increase the incidence of adverse reactions in the central nervous system (mainly headache) and gastrointestinal tract. 3 Avoid using it at the same time with diazepam (valium), phenytoin, warfarin, nifedipine, digoxin, cisapride, quinidine, cyclosporine, caffeine and theophylline. 4 If used at the same time with other drugs, drug interactions may occur. Please consult your doctor or pharmacist for details.

Sealed, store in a dry place.

20 mg

24 months.

Shanghai Sine WANXIANG Pharmaceuticals Co., Ltd.

• Founded in:

  1999-01-25

• Address:

  No. 217, Zhaozhong Road, Qingpu District, Shanghai

• Tax NO.:

  91310000631358877Y

• Registered Funds:

  100 million yuan

• Email:

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