Liranethrin cream
Function and Efficacy
Liranabate is a thiocarbamate antifungal drug and a squalene epoxidase inhibitor. It exerts its antifungal effect by inhibiting the epoxidation reaction of squalene in fungal cell membranes and affecting the synthesis of ergosterol, a component of cell membranes. Liranabate has a strong antifungal effect on skin filamentous fungi (Trichophyton, Microsporum, Epidermophyton), and also shows antifungal effects on other filamentous fungi, dark fungi, and dimorphic fungi.
Ingredients
The main ingredient of this product is liranabate, and its chemical name is N-(6-methoxy-2-pyridyl)-N-methylaminothiocarboxylic acid (5,6,7,8-tetrahydro)-2-naphthyl ester.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| LiranaftateIngredients |
Liranabate is a thiocarbamate antifungal drug and a squalene epoxidase inhibitor. It exerts its antifungal effect by inhibiting the epoxidation reaction of squalene in fungal cell membranes and affecting the synthesis of ergosterol, a component of cell membranes. Liranabate has a strong antifungal effect on skin filamentous fungi (Trichophyton, Microsporum, Epidermophyton), and also shows antifungal effects on other filamentous fungi, dark fungi, and dimorphic fungi. More |
88678-31-3 | 11 |
Appearance
This product is a white to off-white cream.
Indication
Used for the treatment of tinea pedis, tinea corporis, and tinea cruris.
Usage and Dosage
For external use, apply to the affected area once a day.
Adverse Reactions
The incidence of adverse reactions in the safety evaluation of clinical trials of 1,611 subjects was 30 cases (1.86%). Among them, contact dermatitis occurred in 17 cases (1.06%), pruritus in 4 cases (0.25%), redness in 3 cases (0.19%), erythema, pain, and irritation in 2 cases (0.12%). In addition, adverse reactions with an incidence of less than 1% include dermatitis, autosensitivity dermatitis, and flushing.
Precautions
The following patients are contraindicated: 1. Those with a history of allergy to liranabate and other chemical components contained in this product. 2. Those with a history of allergy to other topical antifungal drugs. 3. Patients with clinically difficult to distinguish from skin candidiasis, dyshidrosis, palmoplantar pustulosis, pyoderma and other skin inflammations.
Special Population Medication
Precautions for children: Not yet clear. Precautions for pregnancy and lactation: The safety of this product during pregnancy is not yet clear, so women who are pregnant or preparing for pregnancy should weigh the pros and cons and use it with caution. The safety of this product for lactating women is not yet clear. Precautions for the elderly: Not yet clear.
Drug Interactions
If you are taking other medicines, please consult your physician before using this product.
Storage
Sealed, store in a cool place (not exceeding 20℃).
Packaging Specification
10g:0.2g
Validity Period
24 months
Manufacturer
Shandong Liangfu Pharmaceuticals Co., Ltd.
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Founded in:
1996-01-23 -
Address:
Middle section of Gongming Road, Liangshan County, Shandong Province -
Tax NO.:
91370832613666083W -
Registered Funds:
60.5 million yuan -
Website:
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Email: