Alfacalcidol Soft Capsules

1. Increase the reabsorption of calcium by the small intestine and renal tubules, inhibit parathyroid hyperplasia, reduce the synthesis and release of parathyroid hormone, and inhibit bone resorption. 2. Increase the synthesis of transforming growth factor-β (TGF-β) and insulin-like growth factor-I (IGF-I), and promote the synthesis of collagen and bone matrix protein. 3. Regulate muscle calcium metabolism, promote muscle cell differentiation, enhance muscle strength, increase neuromuscular coordination, and reduce the tendency to fall.

The main ingredient of this product is: Alfacalcidol.

This product is a red transparent capsule containing light yellow or yellow oily liquid.

1. Rickets and osteomalacia. 2. Renal osteodystrophy. 3. Osteoporosis. 4. Hypoparathyroidism.

Oral: Adults, chronic renal insufficiency and osteoporosis: 0.5 μg (2 capsules) each time, once a day, or as directed by a doctor. Children should follow the doctor's advice.

Small doses alone (<1.0 μg/d) generally have no adverse reactions, but long-term high-dose use or combined use with calcium supplements may cause hypercalcemia and hypercalciuria.

It is contraindicated for patients who are allergic to vitamin D and its analogs, have hypercalcemia, or have signs of vitamin D poisoning.

Precautions for children: Data show that the acute toxicity of this product when taken orally by rat pups is higher than that of mature rats. When children take the drug, the serum calcium value should be closely observed. It is advisable to start with a low dose and gradually increase the dose. Be cautious when administering the drug and avoid overdose. Precautions for pregnancy and lactation: 1. Animal experiments have shown that high-dose administration to rats can cause delayed ossification of the fetus. The safety of taking the drug during human pregnancy has not yet been established. For pregnant women and women who may become pregnant, it can only be used when it is judged that the benefits of treatment outweigh the risks. 2. Rat experiments have shown that the drug can be transferred to newborns through lactation, which is about 1/20 of the dose administered to rats. The safety of taking the drug during lactation has not yet been established, and the drug should be avoided during lactation. If it is unavoidable, breastfeeding should be stopped. Precautions for the elderly: Elderly patients generally have low physiological functions, so attention should be paid to adjusting the dosage.

1 Calcium supplements: Combination with calcium supplements may cause elevated blood calcium, so blood calcium should be monitored. 2 Thiazide diuretics: This type of diuretic can promote the kidney's absorption of calcium. There is a risk of hypercalcemia when used together. 3 Digitalis glycosides: Hypercalcemia in patients taking digitalis drugs can easily induce arrhythmias. If this drug is used in combination, blood calcium should be closely monitored. 4 Barbiturates, anticonvulsants: These drugs can accelerate the metabolism of active vitamin D metabolites in the liver and reduce the efficacy of the drug, so the dose of this drug should be appropriately increased. 5 Gastrointestinal absorption inhibitors: Cholestyramine or aluminum-containing antacids can reduce the absorption of this drug. The two should not be taken at the same time. The drugs should be taken one after the other with an interval of 2 hours. <b

Sealed and stored in a cool place.

0.25 μg

36 months

Dalian Aosen Pharmaceutical Co., Ltd.

• Founded in:

  1998-11-12

• Address:

  No. 12 Dingxiang Street, Dalian Huayuankou Economic Zone, Zhuanghe City, Dalian, Liaoning Province

• Tax NO.:

  912102137017959504

• Registered Funds:

  46 million yuan

• Email:

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