Cephalexin and Trimethoprim Capsules
Function and Efficacy
This product inhibits bacterial transpeptidase, prevents the synthesis of bacterial cell walls, and inhibits or kills bacteria. The combination of cephalexin and trimethoprim improves the antibacterial ability, delays the development of drug resistance, and reduces the oral dose.
Ingredients
Each tablet contains 125mg of cephalexin and 25mg of trimethoprim
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| CephalexinIngredients |
By inhibiting bacterial transpeptidase, it prevents the synthesis of bacterial cell walls and inhibits or kills bacteria; when used in combination with trimethoprim, it can enhance antibacterial ability, delay the development of drug resistance, and reduce oral dosage. More |
15686-71-2 | 33 | |
| TrimethoprimIngredients |
By combining it with cephalexin, the antibacterial ability can be improved, the development of drug resistance can be delayed, and the oral dosage can be reduced. More |
738-70-5 | 44 |
Appearance
This product is a capsule, and the contents are white or slightly yellow crystalline powder or granules.
Indication
Used for infections caused by penicillin-resistant Staphylococci, Streptococci, Pneumococci, Escherichia coli, etc.
Usage and Dosage
It is recommended to be taken orally on an empty stomach. Adults take 1-2 tablets at a time, 4 times a day. Children should take a reduced dosage or follow the doctor's advice.
Adverse Reactions
1. Nausea, vomiting, diarrhea and abdominal discomfort are more common. 2. Allergic reactions such as rash and drug fever are rare, and anaphylactic shock may occur occasionally. 3. Neurological reactions such as dizziness, diplopia, tinnitus, and convulsions. 4. Renal damage may occur occasionally during the use of this product. 5. Occasionally, patients have elevated serum aminotransferases and positive Coombs tests. Hemolytic anemia is rare. Neutropenia and pseudomembranous colitis have also been reported. 6. Trimethoprim's interference with folic acid metabolism can produce adverse reactions in the blood system, such as leukopenia, thrombocytopenia or methemoglobin anemia. Generally, leukopenia and thrombocytopenia are mild, and can be recovered by stopping the drug in time. Folic acid preparations can also be added.
Precautions
1. It is contraindicated for those who are allergic to cephalosporins or penicillin. 2. It is contraindicated for those who are allergic to trimethoprim. 3. It is contraindicated for newborns and premature infants. 4. It is contraindicated for patients with severe liver and kidney diseases. 5. It is contraindicated for patients with blood diseases. 6. This product can pass through the placenta and is also excreted through breast milk, so pregnant and lactating women should use it with caution.
Special Population Medication
Precautions for children: It is forbidden to use in newborns and premature infants. Precautions for pregnancy and lactation: This product can pass through the placenta and be excreted through breast milk, so pregnant and lactating women should use it with caution. Precautions for the elderly: It is not clear yet.
Drug Interactions
1. When used in combination with cholestyramine (cholestyramine), the average blood concentration of cephalexin can be reduced. 2. Probenecid can delay the renal excretion of this product, and there are also reports that probenecid can increase the excretion of this product in bile. 3. The chance of leukopenia and thrombocytopenia increases when bone marrow suppressants are used in combination with this product. 4. This product should not be used simultaneously with anti-tumor drugs 2,4-diaminopyrimidines, nor should it be used between courses of treatment with other folic acid antagonists, because it may cause bone marrow aplasia or megaloblastic anemia. 5. Co-use with cyclosporine may increase renal toxicity.
Storage
Keep in a dark, sealed and cool place
Packaging Specification
Cephalexin 62.5 mg, trimethoprim 12.5 mg
Validity Period
Tentative 24 months
Manufacturer
Shenyang Kangzhi Pharmaceutical Co., Ltd.
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Founded in:
1979-11-08 -
Address:
No. 7A1, Kaifa Road, Shenyang Economic and Technological Development Zone -
Tax NO.:
912101001179954513 -
Registered Funds:
12.678899 yuan -
Email: