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Pamidronate Disodium for Injection

Function and Efficacy

This product is a bisphosphonate drug. In vitro and animal tests have shown that it can strongly inhibit the dissolution of hydroxyapatite and the activity of osteoclasts, and has a very significant inhibitory effect on bone absorption. It has an analgesic effect on pain caused by osteolytic bone metastasis of cancer, and can also be used to treat hypercalcemia caused by cancer.

Ingredients

The main ingredient of this product is: Pamidronate disodium. Its chemical name is: 3-amino-1-hydroxypropylidene-1,1-bisphosphonic acid disodium pentahydrate.

Name Description Content CAS NO. Manufacturer
Disodium pamidronateIngredients

This product is a bisphosphonate drug. In vitro and animal tests have shown that it can strongly inhibit the dissolution of hydroxyapatite and the activity of osteoclasts, and has a very significant inhibitory effect on bone absorption. It has an analgesic effect on pain caused by osteolytic bone metastasis of cancer, and can also be used to treat hypercalcemia caused by cancer.

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109552-15-0 28

Appearance

This product is a colorless clear liquid.

Indication

Hypercalcemia complicated by malignancy and bone pain caused by osteolytic cancer metastasis.

Usage and Dosage

Treatment of bone metastasis pain: dilute in 0.9% saline or 5% glucose solution without calcium ions before use. Slow intravenous drip for more than 4 hours, the concentration should not exceed 15mg/125ml, and the drip rate should not be greater than 15-30mg/2 hours. 30-60mg per dose. Treatment of hypercalcemia: Strictly follow the blood calcium concentration and use the drug as appropriate under the guidance of a doctor. Generally: blood calcium mmol/L < 3.03.0-3.53.5-4.04.0mg% < 12.012.0-14.014.0-16.016.0Dose mg

Adverse Reactions

A small number of patients may experience mild nausea, chest pain, chest tightness, dizziness, fatigue, and slight changes in liver and kidney function, and occasionally fever.

Precautions

Patients with a history of allergy to this product and bisphosphonates are contraindicated.

Drug Interactions

Not yet clear.

Storage

Keep tightly closed.

Packaging Specification

30mg

Manufacturer

Shenzhen Salubris Pharmaceuticals Co., Ltd.

  • Founded in:

    1998-11-03
  • Address:

    Area A, 4th Floor, Digital Peninsula, No. 289, Hongliu Road, Fubao Community, Fubao Street, Futian District, Shenzhen
  • Tax NO.:

    91440300708453259J
  • Registered Funds:

    1,114.816535 yuan
  • Website:

  • Email:

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