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Cetirizine Hydrochloride Oral Solution

Function and Efficacy

This product is a selective histamine H1 receptor antagonist. Animal experiments show that this product has no obvious anticholinergic and anti-5-hydroxytryptamine effects, and is not easy to pass through the blood-cerebrospinal fluid barrier to act on the central H1 receptor. When used clinically, the central inhibitory effect is relatively mild.

Ingredients

The main ingredient of this product is cetirizine hydrochloride, and its chemical name is (±)-2-[2-[4-[(4-chlorophenyl)benzyl]-1-piperazinyl]ethoxy]acetic acid dihydrochloride.

Name Description Content CAS NO. Manufacturer
Cetirizine dihydrochlorideIngredients

Selective histamine H1 receptor antagonist, no obvious anticholinergic and anti-5-hydroxytryptamine effect, not easy to pass the blood-cerebrospinal fluid barrier, clinical use of central nervous system inhibitory effect is relatively mild

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83881-52-1 54

Appearance

Colorless clear liquid with slightly sweet taste.

Indication

Used for seasonal or perennial allergic rhinitis, urticaria and skin itching caused by allergens.

Usage and Dosage

Oral administration. Adults or children over 12 years old, 10 ml (10 mg) each time, once a day. Or follow the doctor's advice. If adverse reactions occur, it can be changed to 5 ml (5 mg) in the morning and evening. Children: 6-11 years old: 5 ml (5 mg) in the morning and evening or 10 ml (10 mg) once a day. 2-5 years old: 2.5 ml (2.5 mg) in the morning and evening or 5 ml (5 mg) once a day. Children under 12 years old should take it under the supervision of a doctor or parents.

Adverse Reactions

Adverse reactions are mild and transient, including drowsiness, sleepiness, headache, dizziness, agitation, dry mouth, and gastrointestinal discomfort. Occasionally, aspartate aminotransferase is slightly elevated.

Precautions

It is contraindicated for those who are allergic to this product.

Special Population Medication

Precautions for children: 1. The half-life in the plasma of children aged 6-12 is 6 hours, and in children aged 2-6 is 5 hours, so the plasma metabolism of children is higher than that of normal adults. For the dosage of children aged 2-12, see [Usage and Dosage]. The safety and effectiveness of the drug for children under 2 years old has not been confirmed. 2. When children have liver and kidney damage, the dosage should be reduced for children aged 6-11 years old, and it is not recommended for children under 6 years old. Precautions for pregnancy and lactation: Animal teratogenicity tests show no teratogenic effect. However, this product can enter breast milk and should be prohibited for pregnant and lactating women. Precautions for the elderly: Not yet clear.

Drug Interactions

No interactions with other drugs have been reported, but caution should be exercised when taking sedatives at the same time.

Storage

Keep in a dark, sealed and cool place. Validity period: 24 months.

Packaging Specification

0.1%

Validity Period

24 months

Manufacturer

Beijing Hanmi Pharmaceutical Co., Ltd.

  • Founded in:

    1996-03-27
  • Address:

    No. 10, Tianzhu West Road, Area A, Tianzhu Airport Industrial Zone, Shunyi District, Beijing
  • Tax NO.:

    91110113600048921K
  • Registered Funds:

    630 million yuan
  • Website:

  • Email:

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