Compound paracetamol and methyl paracetamol oral solution
Function and Efficacy
After oral administration, the acetaminophen in this product is rapidly and completely absorbed from the gastrointestinal tract. After absorption, it is evenly distributed in body fluids. 90% to 95% is metabolized in the liver and excreted from the kidneys mainly in the form of binding with glucuronic acid. Chlorpheniramine maleate is slowly absorbed from the gastrointestinal tract after oral administration, with a bioavailability of about 25% to 50% and a protein binding rate of 72%. It takes effect 15 to 60 minutes after oral administration and is mainly metabolized by the liver. Metabolites and unmetabolized drugs are mainly excreted through the kidneys. Dextromethorphan hydrobromide takes effect half an hour after administration and lasts for 6 hours. It is metabolized in the liver. The dextrorphan content in plasma is low, mainly three metabolites: 3-methoxymorphin, 3-hydroxy-17-methylmorphin and 3-hydroxymorphin, which are excreted by the kidneys, including the original and demethylated metabolites.
Ingredients
This product is a compound preparation, and its components are 11.25 mg of acetaminophen, 0.6 mg of dextromethorphan hydrobromide, 93.75 μg of chlorpheniramine maleate, 0.9375 mg of methylephedrine hydrochloride, 2.5 mg of potassium guaiacol sulfonate, 33 μg of riboflavin sodium phosphate, and 1.0 mg of anhydrous caffeine per ml.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Chlorphenamine maleateIngredients |
Oral absorption through the gastrointestinal tract is slow, with a bioavailability of about 25% to 50% and a protein binding rate of 72%. It takes effect 15 to 60 minutes after oral administration and is mainly metabolized by the liver. Metabolites and unmetabolized drugs are mainly excreted through the kidneys. More |
113-92-8 | 28 | |
| Potassium guaiacolsulfonate hemihydrateIngredients |
After oral administration, the acetaminophen in this product is rapidly and completely absorbed from the gastrointestinal tract. After absorption, it is evenly distributed in body fluids. 90% to 95% is metabolized in the liver and excreted from the kidneys mainly in the form of binding with glucuronic acid. Chlorpheniramine maleate is slowly absorbed from the gastrointestinal tract after oral administration, with a bioavailability of about 25% to 50% and a protein binding rate of 72%. It takes effect 15 to 60 minutes after oral administration and is mainly metabolized by the liver. Metabolites and unmetabolized drugs are mainly excreted through the kidneys. Dextromethorphan hydrobromide takes effect half an hour after administration and lasts for 6 hours. It is metabolized in the liver. The dextrorphan content in plasma is low, mainly three metabolites: 3-methoxymorphin, 3-hydroxy-17-methylmorphin and 3-hydroxymorphin, which are excreted by the kidneys, including the original and demethylated metabolites. More |
78247-49-1 | 5 | |
| Riboflavin 5'-Monophosphate Sodium SaltIngredients |
After oral administration, the acetaminophen in this product is rapidly and completely absorbed from the gastrointestinal tract. After absorption, it is evenly distributed in body fluids. 90% to 95% is metabolized in the liver and excreted from the kidneys mainly in the form of binding with glucuronic acid. Chlorpheniramine maleate is slowly absorbed from the gastrointestinal tract after oral administration, with a bioavailability of about 25% to 50% and a protein binding rate of 72%. It takes effect 15 to 60 minutes after oral administration and is mainly metabolized by the liver. Metabolites and unmetabolized drugs are mainly excreted through the kidneys. Dextromethorphan hydrobromide takes effect half an hour after administration and lasts for 6 hours. It is metabolized in the liver. The dextrorphan content in plasma is low, mainly three metabolites: 3-methoxymorphin, 3-hydroxy-17-methylmorphin and 3-hydroxymorphin, which are excreted by the kidneys, including the original and demethylated metabolites. More |
130-40-5 | 8 |
Appearance
This product is a yellow, clear, viscous liquid with a sweet taste.
Indication
Relieve the early symptoms of a cold, such as runny nose, nasal congestion, sneezing, sore throat, cough, sputum, chills, fever, headache, joint pain, myalgia, etc.
Usage and Dosage
Oral administration, 4 times a day. Adult dosage: Oral administration, 4 times a day, 18 ml each time.
Adverse Reactions
Occasionally, rash, skin redness, nausea, vomiting, constipation, loss of appetite, difficulty urinating, dizziness, etc. may occur.
Precautions
1. It is contraindicated for those who have allergic reactions to the ingredients contained in this product. 2. It is contraindicated for patients who have had asthma after taking this product or other anti-cold medicines, antipyretic analgesics containing the same ingredients.
Special Population Medication
Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not yet clear. Precautions for the elderly: This product contains methylephedrine. Elderly patients should follow the doctor's advice when taking the medicine.
Drug Interactions
Patients taking barbiturates, tricyclic antidepressants, and alcohol have a reduced ability to metabolize large amounts of acetaminophen, which can prolong the plasma half-life of acetaminophen. Alcohol can increase the hepatotoxicity caused by acetaminophen overdose.
Storage
Store at room temperature, protected from light, and sealed.
Packaging Specification
100ml, each ml contains 11.25mg of acetaminophen, 0.6mg of dextromethorphan hydrobromide, 93.75μg of chlorpheniramine maleate, 0.9375mg of methylephedrine hydrochloride, 2.5mg of potassium guaiacol sulfonate, 33μg of riboflavin sodium phosphate, and 1.0mg of anhydrous caffeine
Validity Period
Tentatively 24 months.
Manufacturer
Beijing Hanmi Pharmaceutical Co., Ltd.
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Founded in:
1996-03-27 -
Address:
No. 10, Tianzhu West Road, Area A, Tianzhu Airport Industrial Zone, Shunyi District, Beijing -
Tax NO.:
91110113600048921K -
Registered Funds:
630 million yuan -
Website:
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Email: