Chenodeoxycholic acid capsules

The main function of CDCA is to reduce the saturation of cholesterol in bile. After taking CDCA for most patients (when CDCA accounts for 70% of bile salts in bile), lipids return to the micelle state and cholesterol is in an unsaturated state, thereby dissolving and falling off the cholesterol in the stones. Large doses of CDCA (10-15 mg/kg per day) can inhibit the synthesis of cholesterol and increase the secretion of bile in patients with cholelithiasis, but the secretion of bile salts and phospholipids remains unchanged.

Main ingredients and their chemical names: Chenodeoxycholic acid, chemical name 3alpha;, 7alpha;-dihydroxy-5beta;-cholanic acid

This product is a hard capsule, the contents of which are white or light yellow crystalline powder with a peculiar odor.

It is used for cholesterol cholelithiasis and also has certain efficacy on bile pigment stones and mixed stones.

Oral administration, adjust according to the condition, generally 12-15 mg/kg per day based on body weight, twice a day, with meals or milk; obese patients should increase the dosage slightly, up to 18-20 mg/kg per day, and the course of treatment is 6-24 months.

1The most common side effect is diarrhea (30% to 50%), which is characterized by cramps in the lower abdomen followed by watery stools. It is dose-related and disappears after the dose is reduced. Most patients can tolerate it if the dose is gradually increased. 2A small number of patients (30%) may have a transient, reversible increase in AST (SGOT). 3Some patients may experience skin itching, dizziness, nausea, and abdominal distension.

Pregnant women, patients with enteritis or liver disease should not use it.

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not for use by pregnant women. Precautions for the elderly: Not yet clear.

1. Contraceptive pills can increase bile saturation. When using this product for treatment, other birth control measures should be taken as much as possible to avoid affecting the efficacy. 2. Cholestyramine (Cholestyramine), colestipol (Colestipol) and aluminum-containing antacids can bind to CDCA and reduce its absorption. They should not be used together.

Keep away from light, tightly closed, and stored in a dry and cool place.

50 mg

24 months

Liaoning Yuhuang Pharmaceutical Co., Ltd.

• Founded in:

  2005-01-26

• Address:

  No. 5-5, Jialin Road, Sujiatun District, Shenyang City, Liaoning Province

• Tax NO.:

  912101117695668202

• Registered Funds:

  14 million yuan

• Email:

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